Retraction Note: Reversible inhibitor of CRM1 sensitizes glioblastoma cells to radiation by blocking the NF-κB signaling pathway

Abstract

Cancer Cell International (2020) 20:97

https://doi.org/10.1186/s12935-020-01186-y.

Retraction Note

The Editor-in-Chief has retracted this article at the authors’ request. After publication, concerns were raised regarding the data included in the figures. Specifically:

• Fig. 1e 0 Gy images appear to be assembled incorrectly, and the EdU images for 0.125 and 0.25 µM S109 appear highly similar;

• Fig. 2c 0.25 µM 6 Gy image appears highly similar to Fig. 1i (C6 cells, 25 µM GDC-0449) of another article [1] from the same author group;

• Fig. 4b 0 mg/kg S109 10 Gy Day 10 (2nd mouse) and Day 18 (2nd mouse) images appear highly similar;

• Fig. 4e 0 mg/kg S109 10 Gy and 50 mg/kg S109 0 Gy images appear to overlap.

The authors have stated that incorrect images were included in the figure panels during figure preparation. Although the authors believe that these issues do not affect the conclusions of the study, they requested to retract the article to prevent any potential confusion or misinterpretation by readers.

Xuejiao Liu stated on behalf of all authors that all authors agree to this retraction.

1. Tu Y, Niu M, Xie P, et al. Smoothened is a poor prognosis factor and a potential therapeutic target in glioma. Sci Rep. 2017;7:42630. https://doi.org/10.1038/srep42630.

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Authors and Affiliations

1. Insititute of Nervous System Diseases, Affiliated Hospital of Xuzhou Medical University, Xuzhou Medical University, Xuzhou, Jiangsu, China

   Xuejiao Liu, Yiming Tu, Yifeng Wang, Di Zhou, Lin Shi, Guanzheng Liu, Xu Zhang, Huan Li, Shangfeng Gao, Mingshan Niu & Rutong Yu

2. Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

   Xuejiao Liu, Xu Zhang, Shangfeng Gao & Rutong Yu

3. Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

   Yiming Tu

4. Department of Neurosurgery, Suqian Hospital Affiliated to Xuzhou Medical University, Suqian, Jiangsu, China

   Yulong Chong

5. College of Pharmacy, The Ohio State University, Columbus, OH, USA

   Sijin Wu

6. Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China

   Mingshan Niu

Authors

1. Xuejiao LiuView author publications

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2. Yiming TuView author publications

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3. Yifeng WangView author publications

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4. Di ZhouView author publications

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5. Yulong ChongView author publications

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6. Lin ShiView author publications

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7. Guanzheng LiuView author publications

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8. Xu ZhangView author publications

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9. Sijin WuView author publications

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10. Huan LiView author publications

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11. Shangfeng GaoView author publications

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12. Mingshan NiuView author publications

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13. Rutong YuView author publications

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Corresponding author

Correspondence to Rutong Yu.

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The online version of the original article can be found at https://doi.org/10.1186/s12935-020-01186-y.

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Cite this article

Liu, X., Tu, Y., Wang, Y. et al. Retraction Note: Reversible inhibitor of CRM1 sensitizes glioblastoma cells to radiation by blocking the NF-κB signaling pathway. Cancer Cell Int 24, 320 (2024). https://doi.org/10.1186/s12935-024-03508-w

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• Accepted: 13 September 2024

• Published: 18 September 2024

• DOI: https://doi.org/10.1186/s12935-024-03508-w

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