Deana Mohr-Haralampieva, Steve Kappenthuler, Marcus Droege
{"title":"Treating stress urinary incontinence by tissue engineering","authors":"Deana Mohr-Haralampieva, Steve Kappenthuler, Marcus Droege","doi":"10.1038/s44222-024-00246-6","DOIUrl":null,"url":null,"abstract":"Stress urinary incontinence (SUI), a frequently underdiagnosed condition that mainly affects women, lacks effective and long-term treatment options. MUVON Therapeutics has developed a tissue-engineered advanced therapy medicinal product for the treatment of SUI, based on autologous cells, which is being tested in a phase II clinical study — a challenging development effort.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s44222-024-00246-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Stress urinary incontinence (SUI), a frequently underdiagnosed condition that mainly affects women, lacks effective and long-term treatment options. MUVON Therapeutics has developed a tissue-engineered advanced therapy medicinal product for the treatment of SUI, based on autologous cells, which is being tested in a phase II clinical study — a challenging development effort.