Regulatory landscape of a protein kinase-mediated signaling pathway

Abstract

Rice blast fungus Magnaporthe oryzae serves as a model for studying fungal–plant interactions. In a recent phosphoproteomics study, Cruz-Mireles et al. comprehensively analyzed pathogenesis-related phosphorylation in M. oryzae with a focus on the Pmk1 pathway, integrating multiple signaling pathways and identifying new virulence factors. This study has broad implications for our understanding of fungal pathogenesis.