Quaternization of Ethyl Pyridin-2-ylcarbamate with Phenacyl Bromides

IF 0.8 4区 化学 Q4 CHEMISTRY, ORGANIC
D. A. Lomov
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引用次数: 0

Abstract

The reaction of ethyl pyridine-2-ylcarbamate with phenacyl bromides in acetonitrile gave 2-aryl-1-(ethoxycarbonyl)-2-hydroxy-2-phenyl-2,3-dihydro-1H-imidazo[1,2-a]pyridine-4-ium bromides which were con­­verted into 2-arylimidazo[1,2-a]pyridines by heating in acetic anhydride, followed by treatment with potassium carbonate.

Abstract Image

吡啶-2-基氨基甲酸乙酯与苯乙酰溴的季铵化反应
摘要吡啶-2-基氨基甲酸乙酯与苯甲酰溴在乙腈中反应生成 2-芳基-1-(乙氧羰基)-2-羟基-2-苯基-2,3-二氢-1H-咪唑并[1,2-a]吡啶-4-鎓溴化物,在乙酸酐中加热后用碳酸钾处理可将其转化为 2-芳基咪唑并[1,2-a]吡啶。
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来源期刊
CiteScore
1.40
自引率
25.00%
发文量
139
审稿时长
3-6 weeks
期刊介绍: Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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