Multiple cell death modalities and immune response in pulpitis

IF 5.4 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

International endodontic journal Pub Date : 2024-09-10 DOI:10.1111/iej.14145

Ben Wang, Wenwen Li, Weiying Huang, Xuemeng Li, Jiaqi Li, Songtao Shi, Xueli Mao, Xi Wei

引用次数: 0

Abstract

To investigate the level and distribution of apoptosis, pyroptosis, necroptosis, and NETosis in pulpitis with or without necrosis on a basis of histological classification. Additionally, to examine the effect of pulpitis with necrosis (PWN) on the number and activation of peripheral and bone marrow (BM) neutrophils, as well as spleen lymphocytes, in a mouse model of pulpitis.

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牙髓炎的多种细胞死亡模式和免疫反应

根据组织学分类，研究有无坏死的牙髓炎中细胞凋亡、脓毒血症、坏死和NETosis的水平和分布。此外，研究牙髓炎伴坏死（PWN）对小鼠牙髓炎模型中外周和骨髓（BM）中性粒细胞以及脾脏淋巴细胞的数量和活化的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International endodontic journal 医学-牙科与口腔外科

CiteScore

10.20

自引率

28.00%

发文量

195

审稿时长

4-8 weeks

期刊介绍： The International Endodontic Journal is published monthly and strives to publish original articles of the highest quality to disseminate scientific and clinical knowledge; all manuscripts are subjected to peer review. Original scientific articles are published in the areas of biomedical science, applied materials science, bioengineering, epidemiology and social science relevant to endodontic disease and its management, and to the restoration of root-treated teeth. In addition, review articles, reports of clinical cases, book reviews, summaries and abstracts of scientific meetings and news items are accepted. The International Endodontic Journal is essential reading for general dental practitioners, specialist endodontists, research, scientists and dental teachers.