Enzymatic resolution of heterocyclic intermediates for biologically active compound preparation

Phosphorus Sulfur and Silicon and The Related Elements Pub Date : 2024-08-13 DOI:10.1080/10426507.2024.2367033

Anastasy Kolodiazhna, Dmitry Prysiazhnuk, Oleg Kolodiazhnyi

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Abstract

A number of heterocyclic synthons of biologically active compounds were resolved into enantiomers by enzymatic kinetically controlled deracemization in organic media. High enantioselectivities (>98...

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酶解杂环中间体，制备具有生物活性的化合物

在有机介质中，通过酶促动力学控制脱嵌，将一些具有生物活性的杂环合成物分解成对映体。高对映体选择性（>98...

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Phosphorus Sulfur and Silicon and The Related Elements

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