Preparation of polymer composites with electrostatic spinning promotes wound regeneration: A review

IF 1.4 4区物理与天体物理 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY

AIP Advances Pub Date : 2024-09-05 DOI:10.1063/5.0215772

Wanying Yang, Cong Yang, Guanghui Jing, Sen Wang, Jing Li, Xiaonan Zhang, Peng Liu, Ning Yu

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引用次数: 0

Abstract

Wound dressings play a critical role in promoting healing by protecting wounds from external contaminants and providing an optimal environment for tissue regeneration. Traditional dressings, such as gauze and cotton, offer basic physical barriers but lack the ability to maintain a moist wound environment, which is essential for healing. Modern dressings, particularly those incorporating electrospun nanofibers, have emerged as advanced solutions that can sustain moisture, absorb exudate, and support cell growth and migration. This Review covers recent advances in electrospinning technologies and the design of composite materials that integrate natural and synthetic polymers, bioactive agents, and nanomaterials to enhance wound healing. In addition, it highlights key studies demonstrating the efficacy of these composites in various wound models. The primary objective of this Review is to inspire and guide future research endeavors, address existing limitations, and shed light on the promising research prospects in the field of wound healing and tissue regeneration.

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用静电纺丝法制备聚合物复合材料可促进伤口再生：综述

伤口敷料在促进伤口愈合方面起着至关重要的作用，它可以保护伤口免受外部污染物的侵袭，并为组织再生提供最佳环境。传统的敷料，如纱布和棉布，可提供基本的物理屏障，但缺乏维持伤口湿润环境的能力，而这对伤口愈合至关重要。现代敷料，尤其是含有电纺纳米纤维的敷料，已经成为一种先进的解决方案，可以保持湿度、吸收渗出物、支持细胞生长和迁移。本综述介绍了电纺技术和复合材料设计的最新进展，这些材料融合了天然和合成聚合物、生物活性剂和纳米材料，可促进伤口愈合。此外，它还重点介绍了在各种伤口模型中证明这些复合材料功效的主要研究。本综述的主要目的是启发和指导未来的研究工作，解决现有的局限性，并阐明伤口愈合和组织再生领域大有可为的研究前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AIP Advances NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

2.80

自引率

6.20%

发文量

1233

审稿时长

2-4 weeks

期刊介绍： AIP Advances is an open access journal publishing in all areas of physical sciences—applied, theoretical, and experimental. All published articles are freely available to read, download, and share. The journal prides itself on the belief that all good science is important and relevant. Our inclusive scope and publication standards make it an essential outlet for scientists in the physical sciences. AIP Advances is a community-based journal, with a fast production cycle. The quick publication process and open-access model allows us to quickly distribute new scientific concepts. Our Editors, assisted by peer review, determine whether a manuscript is technically correct and original. After publication, the readership evaluates whether a manuscript is timely, relevant, or significant.