New Cross-Conjugated Chlorocyclopentenone Derivatives Containing an Amino Acid Fragment at C3

Abstract

The reaction of 5-allenyl-2,3,5-trichlorocyclopentenone with glycine, L-methionine, L-leucine, and L-tyrosine methyl esters gave the corresponding Ad_NE adducts, and the subsequent oxidative cleavage of the allene fragment afforded new 4-carboxymethylidene derivatives.