A Simple and Facile Conjugate Addition of Cyclic and Acyclic 1,3-Diketones to β-Nitrostyrenes

IF 2.8 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2024-08-13 DOI:10.1002/ajoc.202400355

Dharti Mistry, Nikunjana Benjamin Macwan, Payal Malvi, Dandamudi V. Lenin

引用次数: 0

Abstract

A simple synthesis of 3-hydroxy-2-(2-nitro-1-arylethyl)cyclohex-2-en-1-ones, 3-hydroxy-5,5-dimethyl-2-(2-nitro-1-arylethyl)cyclohex-2-en-1-ones and 4-hydroxy-3-(2-nitro-1-arylethyl)pent-3-en-2-ones via conjugate addition of cyclic 1,3-diketones, 1,3-cyclohexanedione and 5,5-dimethyl-1,3-cyclohexanedione and acyclic 1,3-diketone, pentane-2,4-dione to β-Nitrostyrenes were reported. This methodology is pleasing with reliability and scalability with gram scale products that can be synthesized.

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环状和非环状 1,3-二酮与β-硝基苯炔的简单易行共轭加成反应

:3-羟基-2-(2-硝基-1-芳基)环己-2-烯-1-酮、3-羟基-5,5-二甲基-2-(2-硝基-1-芳基)环己-2-烯-1-酮和 4-羟基-3-(2-硝基-1-芳基)戊-3-烯-2-酮的简单合成，通过环状 1、3-二酮、1,3-环己二酮和 5,5-二甲基-1,3-环己二酮以及无环 1,3-二酮、戊烷-2,4-二酮与β-硝基苯烯的共轭加成。该方法具有可靠性和可扩展性，可合成克级产品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.