Early vs. interval approach to laparoscopic cholecystectomy for acute cholecystitis: a retrospective observational study from Pakistan

IF 1.6 4区医学 Q2 SURGERY

Frontiers in Surgery Pub Date : 2024-09-06 DOI:10.3389/fsurg.2024.1462885

Sandesh Raja, Azzam Ali, Dileep Kumar, Adarsh Raja, Khursheed Ahmed Samo, Amjad Siraj Memon

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Abstract

BackgroundLaparoscopic cholecystectomy (LC) is the preferred treatment for acute cholecystitis (AC). However, the optimal timing for LC in AC management remains uncertain, with early cholecystectomy (EC) and interval cholecystectomy (IC) being two common approaches influenced by various factors.MethodsThis retrospective study, conducted at a tertiary care teaching hospital in Karachi, Pakistan, aimed to compare the outcomes of EC vs. IC for AC management. Patient data from January 2019 to September 2019 were analyzed with a focus on operative complications, duration of surgery, and postoperative hospital stay. The inclusion criteria were based on the Tokyo Guidelines, and patients underwent LC within 3 days of symptom onset in the EC group and after 6 weeks in the IC group.ResultsAmong 147 eligible patients, 100 underwent LC (50 in each group). No significant differences were observed in the sex distribution or mean age between the two groups. The EC group experienced fewer operative complications (12%) than the IC group (34%), with statistically significant differences observed. Nevertheless, no substantial variations in operative time or postoperative hospital stay were observed between the groups.ConclusionReduced complications in the EC group underscore its safety and efficacy. Nonetheless, further validation through multicenter studies is essential to substantiate these findings.

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急性胆囊炎腹腔镜胆囊切除术的早期与间歇方法：巴基斯坦的一项回顾性观察研究

背景腹腔镜胆囊切除术（LC）是急性胆囊炎（AC）的首选治疗方法。然而，LC 治疗急性胆囊炎的最佳时机仍不确定，早期胆囊切除术（EC）和间歇性胆囊切除术（IC）是受各种因素影响的两种常见方法。方法这项回顾性研究在巴基斯坦卡拉奇的一家三级医疗教学医院进行，旨在比较 EC 与 IC 治疗急性胆囊炎的结果。研究分析了 2019 年 1 月至 2019 年 9 月的患者数据，重点关注手术并发症、手术持续时间和术后住院时间。纳入标准以《东京指南》为基础，EC组患者在症状出现后3天内接受LC治疗，IC组患者在6周后接受LC治疗。两组患者的性别分布和平均年龄无明显差异。EC组出现的手术并发症（12%）少于IC组（34%），差异有统计学意义。结论 EC 组并发症的减少凸显了其安全性和有效性。尽管如此，通过多中心研究进一步验证这些发现还是非常必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Surgery Medicine-Surgery

CiteScore

1.90

自引率

11.10%

发文量

1872

审稿时长

12 weeks

期刊介绍： Evidence of surgical interventions go back to prehistoric times. Since then, the field of surgery has developed into a complex array of specialties and procedures, particularly with the advent of microsurgery, lasers and minimally invasive techniques. The advanced skills now required from surgeons has led to ever increasing specialization, though these still share important fundamental principles. Frontiers in Surgery is the umbrella journal representing the publication interests of all surgical specialties. It is divided into several “Specialty Sections” listed below. All these sections have their own Specialty Chief Editor, Editorial Board and homepage, but all articles carry the citation Frontiers in Surgery. Frontiers in Surgery calls upon medical professionals and scientists from all surgical specialties to publish their experimental and clinical studies in this journal. By assembling all surgical specialties, which nonetheless retain their independence, under the common umbrella of Frontiers in Surgery, a powerful publication venue is created. Since there is often overlap and common ground between the different surgical specialties, assembly of all surgical disciplines into a single journal will foster a collaborative dialogue amongst the surgical community. This means that publications, which are also of interest to other surgical specialties, will reach a wider audience and have greater impact. The aim of this multidisciplinary journal is to create a discussion and knowledge platform of advances and research findings in surgical practice today to continuously improve clinical management of patients and foster innovation in this field.

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