Comprehensive Assessment of Herbicide Toxicity on Navicula sp. Algae: Effects on Growth, Chlorophyll Content, Antioxidant System, and Lipid Metabolism

IF 4.9 2区医学 Q1 CHEMISTRY, MEDICINAL

Marine Drugs Pub Date : 2024-08-28 DOI:10.3390/md22090387

Chunyan Zheng, Jie Yang, Yunting Wang, Waqas Ahmed, Amir Khan, Jiannan Li, Jiechang Weng, Sajid Mehmood, Weidong Li

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Abstract

This study investigated the effects of herbicide exposure on Navicula sp. (MASCC-0035) algae, focusing on growth density, chlorophyll content, antioxidant system, and lipid metabolism. Navicula cultures were exposed to different concentrations of atrazine (ATZ), glyphosate (Gly), and acetochlor (ACT) for 96 h. Results showed a significant decrease in cell numbers, with higher herbicide concentrations having the most noticeable impacts. For instance, Gly-G2 had reduced cell populations by 21.00% at 96 h. Chlorophyll content varied, with Gly having a greater impact on chlorophyll a compared to ATZ and ACT. Herbicide exposure also affected the antioxidant system, altering levels of soluble sugar, soluble protein, and reactive oxygen species (ROS). Higher herbicide rates increased soluble sugar content (e.g., ATZ, Gly, and ACT-G2 had increased by 14.03%, 19.88%, and 19.83%, respectively, at 72 h) but decreased soluble protein content, notably in Gly-G2 by 11.40%, indicating cellular stress. Lipid metabolism analysis revealed complex responses, with changes in free proline, fatty acids, and lipase content, each herbicide exerting distinct effects. These findings highlight the multifaceted impacts of herbicide exposure on Navicula algae, emphasizing the need for further research to understand ecological implications and develop mitigation strategies for aquatic ecosystems.

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除草剂对 Navicula sp：对生长、叶绿素含量、抗氧化系统和脂质代谢的影响

本研究调查了除草剂暴露对Navicula sp. (MASCC-0035)藻类的影响，重点是生长密度、叶绿素含量、抗氧化系统和脂质代谢。将褐藻培养物暴露于不同浓度的阿特拉津（ATZ）、草甘膦（Gly）和乙草胺（ACT）中 96 小时，结果显示细胞数量显著减少，除草剂浓度越高，影响越明显。叶绿素含量各不相同，与 ATZ 和 ACT 相比，草甘膦对叶绿素 a 的影响更大。除草剂暴露也会影响抗氧化系统，改变可溶性糖、可溶性蛋白质和活性氧（ROS）的水平。除草剂使用率越高，可溶性糖含量越高（例如，72 小时后，ATZ、Gly 和 ACT-G2 的可溶性糖含量分别增加了 14.03%、19.88% 和 19.83%），但可溶性蛋白质含量却降低了，尤其是 Gly-G2 降低了 11.40%，这表明细胞受到了压力。脂质代谢分析显示了复杂的反应，游离脯氨酸、脂肪酸和脂肪酶含量都发生了变化，每种除草剂都产生了不同的影响。这些研究结果突显了暴露于除草剂对纳维藻的多方面影响，强调了进一步研究的必要性，以了解生态影响并为水生生态系统制定缓解策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Marine Drugs 医学-医药化学

CiteScore

9.60

自引率

14.80%

发文量

671

审稿时长

1 months

期刊介绍： Marine Drugs (ISSN 1660-3397) publishes reviews, regular research papers and short notes on the research, development and production of drugs from the sea. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible, particularly synthetic procedures and characterization information for bioactive compounds. There is no restriction on the length of the experimental section.