Synthesis of fluorinated six-membered nitrogen heterocycles using microwave irradiation

IF 1.4 4区 化学 Q3 CHEMISTRY, ORGANIC
Chandra Prakash, Ram Singh
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引用次数: 0

Abstract

The presence of one or more fluorine atoms in six-membered nitrogen heterocycles significantly impacts their chemical and physical properties, making them important in various applications, including pharmaceuticals and agrochemicals. This review, therefore, surveys the recent advances (mostly from 2010 onwards) in the synthesis of fluorinated six-membered N-heterocyclic compounds, including both the use of fluorinated starting materials and the introducing of fluorine atoms in the heterocyclic core and in either case exploring the benefits of microwave-assisted processes.

Abstract Image

利用微波辐照合成氟化六元氮杂环
六元氮杂环中含有一个或多个氟原子会显著影响其化学和物理性质,使其在制药和农用化学品等各种应用中发挥重要作用。因此,本综述概述了合成含氟六元氮杂环化合物的最新进展(主要是 2010 年以来的进展),包括使用含氟起始材料和在杂环核心中引入氟原子,以及在这两种情况下探索微波辅助工艺的益处。
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来源期刊
CiteScore
2.90
自引率
13.30%
发文量
98
审稿时长
1 months
期刊介绍: The international journal Chemistry of Heterocyclic Compounds publishes original papers, short communications, reviews, and mini-reviews dealing with problems in the field of heterocyclic chemistry in Russian and English. The Journal also publishes reviews and annotations on new books and brief reports on conferences in the field of heterocyclic chemistry, as well as commemo­ra­tives dedicated to prominent heterocyclic chemists.
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