Design, Synthesis, and biological evaluation of copper(II) complexes with phenanthroline-based ligands as potential anticancer agents

IF 2.2 4区 化学 Q3 CHEMISTRY, INORGANIC & NUCLEAR
Dongdong Li, Hui Wang, Cheng Tan, Linlin Dai, Shuang Zhi, Zibo Yang
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引用次数: 0

Abstract

We have synthesized and characterized five copper(II) complexes, [Cu(L1)(alanine)(NO3)]·2H2O (1), [Cu(L1)(methionine)(H2O)]NO3·4H2O (2), [Cu(L2)(glycine)] NO3·3H2O (3), [Cu(L2)(alanine)Cl]·2H2O (4)...
作为潜在抗癌剂的菲罗啉基配体铜(II)配合物的设计、合成和生物学评价
我们合成并鉴定了五种铜(II)配合物:[Cu(L1)(丙氨酸)(NO3)]-2H2O (1)、[Cu(L1)(蛋氨酸)(H2O)]NO3-4H2O (2)、[Cu(L2)(甘氨酸)] NO3-3H2O (3)、[Cu(L2)(丙氨酸)Cl]-2H2O (4)。
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来源期刊
Journal of Coordination Chemistry
Journal of Coordination Chemistry 化学-无机化学与核化学
CiteScore
3.60
自引率
10.50%
发文量
171
审稿时长
3.2 months
期刊介绍: The Journal of Coordination Chemistry publishes the results of original investigations of coordination complexes, loosely defined as the interactions of organic or inorganic ligands with metal centres. Original investigations may involve syntheses, structures, physical and chemical properties, kinetics and mechanisms of reactions, calculations and applications of coordination compounds. The applications may involve bioinorganic, organometallic, catalytic, solid state/materials, coordination chemistry of nanostructured surfaces and medicinal studies. The Journal publishes original manuscripts, communications and reviews. Original manuscripts are expected to provide a clear contribution to the advance of coordination chemistry. Communications are short manuscripts with an urgency that requires rapid publication. Reviews are welcome in all areas of coordination chemistry and may focus on the metal, ligand or applications. Reviews of emerging areas of coordination chemistry should be developed fully from the basics, carefully relating the topic to the field in general. Reviews of well established subjects should collect developments from the literature and take a critical view of recent work.
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