IgG4-related disease in the nervous system

IF 2.4 Q2 CLINICAL NEUROLOGY

PRACTICAL NEUROLOGY Pub Date : 2024-09-12 DOI:10.1136/pn-2020-002863

Lu Yang, R J Paul Smith, Neil J Scolding, Claire M Rice

引用次数: 0

Abstract

IgG4-related disease (IgG4-RD) is a recently described multisystemic disorder with a spectrum of manifestations that continue to be described. Nonetheless, there are recognised distinct patterns of disease. Neurological involvement is rare, particularly in isolation, but IgG4-RD may present with orbital disease, hypophysitis or pachymeningitis. Typically, it is highly responsive to treatment. This review highlights neurological manifestations of IgG4-RD and emphasises the importance of a high index of clinical suspicion to facilitate investigation and appropriate management, avoiding irreversible tissue damage and neurological dysfunction. We present a treatment algorithm for suggested management of IgG4-RD affecting the nervous system. No data are available.

查看原文本刊更多论文

神经系统 IgG4 相关疾病

IgG4 相关疾病（IgG4-RD）是最近描述的一种多系统疾病，其表现形式多种多样，目前仍在不断描述之中。不过，这种疾病有公认的独特模式。神经系统受累的情况很少见，尤其是在单独发病的情况下，但 IgG4-RD 可能伴有眼眶疾病、脑垂体炎或脑桥炎。通常情况下，该病对治疗反应强烈。本综述重点介绍了 IgG4-RD 的神经系统表现，并强调了临床高度怀疑的重要性，以促进检查和适当的治疗，避免不可逆转的组织损伤和神经功能障碍。我们为影响神经系统的 IgG4-RD 提出了一种治疗算法。暂无数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

PRACTICAL NEUROLOGY Medicine-Neurology (clinical)

CiteScore

3.70

自引率

3.60%

发文量

113

期刊介绍： The essential point of Practical Neurology is that it is practical in the sense of being useful for everyone who sees neurological patients and who wants to keep up to date, and safe, in managing them. In other words this is a journal for jobbing neurologists - which most of us are for at least part of our time - who plough through the tension headaches and funny turns week in and week out. Primary research literature potentially relevant to routine clinical practice is far too much for any neurologist to read, let alone understand, critically appraise and assimilate. Therefore, if research is to influence clinical practice appropriately and quickly it has to be digested and provided to neurologists in an informative and convenient way.