Advances in synthesis and anticancer applications of organo-tellurium compounds

IF 4.1 3区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Reviews in Inorganic Chemistry Pub Date : 2024-08-30 DOI:10.1515/revic-2024-0039

Fadhil Farhood M. Al-joborae, Sawsan S. Al-Rawi, Ahmad H. Ibrahim, Abbas Washeel Salman, Muhammad Adnan Iqbal

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引用次数: 0

Abstract

The present review deeply delves the major methods for the synthesis of organotellurium compounds along with their biological significance. Elaboration of various precursors (ligands) including Schiff bases, naphthoquinones, amino acids, β-hydroxy alkylated compounds, β-phenyltelluro alcohols, β-aryltelluro amines, β-aryl-chalcogenium azides, chalcogenobiotin, benzenesulfonamide, carbonic anhydrase, and Sulpha compounds has been briefly described. Furthermore, the article investigates their possible biological uses, specifically as antioxidant and anticancer agents while comparing their effectiveness with their respective ligands and with the standard medications in terms IC50 values. All types of details are haunted to make the information a priceless resource for researchers who wish to probe deeper into and examine the diverse roles that organotellurium complexes play in biological settings.

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有机碲化合物的合成和抗癌应用进展

本综述深入探讨了合成有机碲化合物的主要方法及其生物学意义。文章简要介绍了各种前体（配体），包括希夫碱、萘醌、氨基酸、β-羟基烷基化化合物、β-苯基碲醇、β-芳基碲胺、β-芳基羰基叠氮化物、羰基生物素、苯磺酰胺、碳酸酐酶和 Sulpha 化合物。此外，文章还研究了它们可能的生物用途，特别是作为抗氧化剂和抗癌剂的用途，同时比较了它们与各自配体和标准药物在 IC50 值方面的有效性。所有类型的细节都蕴含其中，使这些信息成为研究人员深入探讨和研究有机碲复合物在生物环境中发挥的各种作用的无价资源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reviews in Inorganic Chemistry 化学-分析化学

CiteScore

7.30

自引率

4.90%

发文量

审稿时长

1 months

期刊介绍： Reviews in Inorganic Chemistry (REVIC) is a quarterly, peer-reviewed journal that focuses on developments in inorganic chemistry. Technical reviews offer detailed synthesis protocols, reviews of methodology and descriptions of apparatus. Topics are treated from a synthetic, theoretical, or analytical perspective. The editors and the publisher are committed to high quality standards and rapid handling of the review and publication process. The journal publishes all aspects of solid-state, molecular and surface chemistry. Topics may be treated from a synthetic, theoretical, or analytical perspective. The editors and the publisher are commited to high quality standards and rapid handling of the review and publication process. Topics: -Main group chemistry- Transition metal chemistry- Coordination chemistry- Organometallic chemistry- Catalysis- Bioinorganic chemistry- Supramolecular chemistry- Ionic liquids