Engineering probiotic Escherichia coli Nissle 1917 to block transfer of multiple antibiotic resistance genes by exploiting a type I CRISPR-Cas system

IF 3.9 2区生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Applied and Environmental Microbiology Pub Date : 2024-09-10 DOI:10.1128/aem.00811-24

Mengdie FangRuiting ZhangChenyu WangZhizhi LiuMingyue FeiBiao TangHua YangDongchang Sun1College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China2School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, Zhejiang, China3State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China4Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, ChinaYvonne Nygård

引用次数: 0

Abstract

Applied and Environmental Microbiology, Ahead of Print.

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利用 I 型 CRISPR-Cas 系统工程改造益生菌大肠杆菌 Nissle 1917，阻止多种抗生素抗性基因的转移

应用与环境微生物学》，提前出版。

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来源期刊

Applied and Environmental Microbiology 生物-生物工程与应用微生物

CiteScore

7.70

自引率

2.30%

发文量

730

审稿时长

1.9 months

期刊介绍： Applied and Environmental Microbiology (AEM) publishes papers that make significant contributions to (a) applied microbiology, including biotechnology, protein engineering, bioremediation, and food microbiology, (b) microbial ecology, including environmental, organismic, and genomic microbiology, and (c) interdisciplinary microbiology, including invertebrate microbiology, plant microbiology, aquatic microbiology, and geomicrobiology.