Zeolitic Imidazolate Frameworks Based Anticancer Drug Delivery System Associated with Dual Action of Surface Charge and Lewis Base Ligand (Adv. Therap. 9/2024)

Abstract

Zeolitic imidazolate frameworks (ZIFs) are emerging as a promising nanocarrier platform for drug delivery. In article 2300447, Yongheng Zhu, Xinghua Gao, Yuan Zhang, and co-workers elucidate the crucial role of surface charge and Lewis-base ligand in determining cytotoxicity, cellular uptake, and intracellular release. These findings offer valuable insights for the screening of ZIF-based nanocarriers.