Why graph theory deserves more focus. Comment on “Connectivity analyses for task-based fMRI” by Huang et al.

Abstract

Huang et al. have conducted a thorough examination of methodologies used for identifying and analyzing functional connectivity using task-based fMRI. Their review adeptly describes current approaches without bias or preference. In this commentary, we explain why we believe that graph theory is the optimal approach for studying neural mechanisms associated with complex behaviors and cognitive processes that are engaged during task-based fMRI.