Delafloxacin, an alternative treatment for levofloxacin-resistant staphylococci in osteoarticular infections: To use or not to use?

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-09-02 DOI:10.1016/j.diagmicrobio.2024.116518

Caroline Loïez , Audrey Charlet , Fanny Lemonnier , Henri Migaud , Éric Senneville , Claire Duployez , Frédéric Wallet

引用次数: 0

Abstract

Susceptibility of delafloxacin on 199 osteoarticular levofloxacin-resistant staphylococci strains was reported in 49% and 1% using SSTI S. aureus breakpoint (0.25 mg/L) and general S. aureus breakpoint (0.016 mg/L) respectively. Fifty percents levofloxacin-resistant staphylococci showed resistance to delafloxacin using CA-SFM/EUCAST recommendations. Microbiological societies should define new breakpoints especially for CoNS.

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地拉沙星，治疗骨关节感染中耐药左氧氟沙星葡萄球菌的替代疗法：用还是不用？

采用SSTI金黄色葡萄球菌断点（0.25 mg/L）和普通金黄色葡萄球菌断点（0.016 mg/L）对199株骨关节左氧氟沙星耐药的金黄色葡萄球菌进行检测，结果显示分别有49%和1%的金黄色葡萄球菌对地氟沙星产生了耐药性。根据 CA-SFM/EUCAST 的建议，50% 的左氧氟沙星耐药葡萄球菌对地氟沙星产生了耐药性。微生物学会应定义新的断点，尤其是针对CoNS的断点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.