Astrocytic adenosine A₁ receptors: a new potential target for treating sepsis-associated encephalopathy.

IF 3 4区医学 Q2 NEUROSCIENCES

Purinergic Signalling Pub Date : 2024-09-06 DOI:10.1007/s11302-024-10049-4

Si-Le Liu, Yong Tang

引用次数: 0

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星形胶质细胞腺苷 A1 受体：治疗败血症相关脑病的潜在新靶点

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来源期刊

Purinergic Signalling 医学-神经科学

CiteScore

6.60

自引率

17.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Nucleotides and nucleosides are primitive biological molecules that were utilized early in evolution both as intracellular energy sources and as extracellular signalling molecules. ATP was first identified as a neurotransmitter and later as a co-transmitter with all the established neurotransmitters in both peripheral and central nervous systems. Four subtypes of P1 (adenosine) receptors, 7 subtypes of P2X ion channel receptors and 8 subtypes of P2Y G protein-coupled receptors have currently been identified. Since P2 receptors were first cloned in the early 1990’s, there is clear evidence for the widespread distribution of both P1 and P2 receptor subtypes in neuronal and non-neuronal cells, including glial, immune, bone, muscle, endothelial, epithelial and endocrine cells.

Astrocytic adenosine A1 receptors: a new potential target for treating sepsis-associated encephalopathy.

Astrocytic adenosine A₁ receptors: a new potential target for treating sepsis-associated encephalopathy.