A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution

IF 2.4 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Polyhedron Pub Date : 2024-08-17 DOI:10.1016/j.poly.2024.117190

Xi-Xi Wang , Rui-Peng Liu , Ai-Ling Cheng , Qing-Song Xue , En-Qing Gao

引用次数: 0

Abstract

In this work, a composite material (ACE@UiO-66-NH₂) has been synthesized conveniently by loading a cysteine-responsive molecular probe Acrylic acid 3-acetyl-2-oxo-2H-chromen-7-yl ester (ACE) on a UiO-type zirconium-based metal–organic framework (UiO-66-NH₂). Furthermore, the resulting ACE@UiO-66-NH₂ demonstrated to be a fluorescent turn-on probe for selective recognition of Cys from other amino acids in aqueous HEPES buffer systems. Additionally, the proposed recognition mechanism has been confirmed by ¹H NMR and TLC. The study provided a promising approach to rationally design MOF-based fluorescent sensor for Cys in aqueous system.

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负载香豆素客体的金属有机框架复合材料是一种用于检测水溶液中半胱氨酸的开启式发光传感器

在这项研究中，通过将半胱氨酸响应分子探针丙烯酸 3-乙酰基-2-氧代-2H-色烯-7-基酯（ACE）负载在 UiO 型锆基金属有机框架（UiO-66-NH2）上，方便地合成了一种复合材料（ACE@UiO-66-NH2）。此外，所产生的 ACE@UiO-66-NH2 被证明是一种荧光开启探针，可在 HEPES 水缓冲体系中从其他氨基酸中选择性地识别 Cys。此外，1H NMR 和 TLC 也证实了所提出的识别机制。该研究为合理设计基于 MOF 的水体系中 Cys 的荧光传感器提供了一种可行的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polyhedron 化学-晶体学

CiteScore

4.90

自引率

7.70%

发文量

515

审稿时长

2 months

期刊介绍： Polyhedron publishes original, fundamental, experimental and theoretical work of the highest quality in all the major areas of inorganic chemistry. This includes synthetic chemistry, coordination chemistry, organometallic chemistry, bioinorganic chemistry, and solid-state and materials chemistry. Papers should be significant pieces of work, and all new compounds must be appropriately characterized. The inclusion of single-crystal X-ray structural data is strongly encouraged, but papers reporting only the X-ray structure determination of a single compound will usually not be considered. Papers on solid-state or materials chemistry will be expected to have a significant molecular chemistry component (such as the synthesis and characterization of the molecular precursors and/or a systematic study of the use of different precursors or reaction conditions) or demonstrate a cutting-edge application (for example inorganic materials for energy applications). Papers dealing only with stability constants are not considered.