Taylor Semeniuk, Ty Dudas, Esther Okeh, Tanner Felesky, Jean-Denys Hamel
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引用次数: 0
Abstract
A photocatalytic process was devised to synthesize monofluoroalkenes via defluorinative functionalization of allylic difluorides. N-Alkylanilines are used as precursors to α-aminoalkyl radicals, which undergo regioselective addition to allylic difluorides, and subsequent SET and fluoride elimination produce monofluoroalkenes. C-C bond formation on the aniline is site-selective for the least substituted carbon α to nitrogen.
期刊介绍:
The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.