The immune health metric as an indicator of health and disease

IF 29.4 1区医学 Q1 RHEUMATOLOGY

Nature Reviews Rheumatology Pub Date : 2024-09-02 DOI:10.1038/s41584-024-01162-0

Satoshi Kubo, Yoshiya Tanaka

引用次数: 0

Abstract

Immune health has been considered impossible to assess through the use of traditional biomarkers. The newly devised immune health metric (IHM) integrates diverse biological data to quantify immune function, offering a comprehensive indicator for the evaluation of immune health. The potential of the IHM to distinguish healthy individuals from patients with monogenic or polygenic immune-mediated diseases might lead to revolutionary changes in treatment strategies for rheumatic diseases.

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作为健康和疾病指标的免疫健康指标

免疫健康一直被认为无法通过使用传统的生物标志物来评估。新设计的免疫健康指标（IHM）整合了各种生物数据来量化免疫功能，为评估免疫健康提供了一个综合指标。IHM可以将健康人与单基因或多基因免疫介导疾病患者区分开来，这可能会给风湿病的治疗策略带来革命性的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Rheumatology 医学-风湿病学

CiteScore

29.90

自引率

0.90%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.