Nyctanthes arbor-tristis Linn. (Night Jasmine): extraction techniques, phytochemical constituents, and biological impacts of extracts and essential oil

IF 3.4 Q2 PHARMACOLOGY & PHARMACY
Kaliyaperumal Ashokkumar, Meenakchisundaram Dharshini, Thirugnanam Janani, Venkatasubramaniyan Shrravani Sri, Ramachandran Subhasidha
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引用次数: 0

Abstract

Background

Nyctanthes arbor-tristis Linn. is a small, sacred ornamental tree used in prayer. It is renowned throughout India for its aromatic white blossoms. The entire plant was widely used for several health applications particularly root and bark were used to treat fever and cough, respectively. Also, the leaf was used for managing fever and diabetes, and its cholagogue, diaphoretic, and anthelmintic properties.

Main text

The current review aimed to comprehensively analyze the botanical characteristics, phytochemistry, and pharmacology of N. arbor-tristis essential oil (NAEO) and extracts. Additionally, it wants to emphasize the latest advancements in phytochemistry and pharmacology related to this aromatic plant. Depending on the variety, origin, and plant parts used, the NAEO yield ranged from 0.002 to 0.10% on a dry basis. The NAEO has been investigated in only a few research studies and resulted, in the predominant levels of phytol and methyl palmitate chemical compounds. Furthermore, the NAEO was found to have significant volatile chemical constituents, including geranylgeraniol, phytoene, nonadecane, linalool, and various other miscellaneous chemical components. The plant extracts and NAEO have numerous biological properties, including antioxidant, antimicrobial, anticancer, anti-inflammatory, analgesic, larvicidal, and other miscellaneous activities.

Conclusion

This paper analyzes and summarizes the diverse research potential associated with N. arbor-tristis. The results of the present study suggested that most of the biological and pharmacological investigations were carried out without including dosage, positive controls, and negative controls. Furthermore, several pharmacological investigations were exclusively carried out using cell lines and animal models. Hence, the following research endeavors aimed at assessing the medicinal properties of NAEO and extracts in human subjects would broaden the scope of its utilization.

Graphical abstract

Nyctanthes arbor-tristis Linn.(夜来香):提取技术、植物化学成分以及提取物和精油的生物影响
背景Nyctanthes arbor-tristis Linn.是一种用于祈祷的神圣观赏小树。它以芳香的白色花朵而闻名印度。整株植物被广泛用于多种保健用途,特别是根和树皮,分别用于治疗发烧和咳嗽。本综述旨在全面分析 N. arbor-tristis 精油(NAEO)和提取物的植物学特征、植物化学和药理学。此外,它还希望强调与这种芳香植物相关的植物化学和药理学的最新进展。根据品种、产地和植物部位的不同,NAEO 的干基产量在 0.002% 到 0.10% 之间。仅有少数研究对 NAEO 进行了调查,结果表明其主要含有植醇和棕榈酸甲酯化学成分。此外,还发现 NAEO 含有大量挥发性化学成分,包括香叶醇、植物烯、壬烷、芳樟醇和其他各种化学成分。植物提取物和 NAEO 具有多种生物特性,包括抗氧化、抗菌、抗癌、消炎、镇痛、杀幼虫剂和其他多种活性。本研究的结果表明,大多数生物和药理研究都是在不包括剂量、阳性对照和阴性对照的情况下进行的。此外,有几项药理研究仅使用细胞系和动物模型进行。因此,接下来的研究工作旨在评估 NAEO 和提取物在人体中的药用特性,这将扩大其应用范围。
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来源期刊
自引率
0.00%
发文量
44
审稿时长
23 weeks
期刊介绍: Future Journal of Pharmaceutical Sciences (FJPS) is the official journal of the Future University in Egypt. It is a peer-reviewed, open access journal which publishes original research articles, review articles and case studies on all aspects of pharmaceutical sciences and technologies, pharmacy practice and related clinical aspects, and pharmacy education. The journal publishes articles covering developments in drug absorption and metabolism, pharmacokinetics and dynamics, drug delivery systems, drug targeting and nano-technology. It also covers development of new systems, methods and techniques in pharmacy education and practice. The scope of the journal also extends to cover advancements in toxicology, cell and molecular biology, biomedical research, clinical and pharmaceutical microbiology, pharmaceutical biotechnology, medicinal chemistry, phytochemistry and nutraceuticals.
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