SIADH and mixed delirium following the abrupt cessation of long-acting benzodiazepines: a case report.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2024-09-02 eCollection Date: 2024-09-01 DOI:10.1093/omcr/omae098

Ahmad F Alenezi, Ahmed Alnuaimi, Dan Liberman

引用次数: 0

Abstract

Benzodiazepines (BZDs) are among the most commonly used medications due to their efficacy and rapid onset of action. Although they offer significant therapeutic benefits in treating various psychiatric and neurological conditions, their clinical utility is limited by substantial risks, including dependency and withdrawal symptoms. The syndrome of inappropriate antidiuretic hormone secretion (SIADH) has been linked to BZD withdrawal. In this case report, we examine the case of an elderly female presented with a mixed delirium and SIADH following the abrupt cessation of long-term clonazepam therapy. To our knowledge, this is the second case that documents a link between SIADH and BZD withdrawal.

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突然停用长效苯并二氮杂卓后的 SIADH 和混合谵妄：一份病例报告。

苯二氮卓类药物（BZDs）因其疗效好、起效快而成为最常用的药物之一。虽然它们在治疗各种精神和神经疾病方面具有明显的疗效，但其临床应用却受到很大风险的限制，包括依赖性和戒断症状。抗利尿激素分泌失调综合征（SIADH）与 BZD 戒断有关。在本病例报告中，我们研究了一名老年女性在突然停止长期氯硝西泮治疗后出现混合谵妄和 SIADH 的病例。据我们所知，这是第二例将 SIADH 与 BZD 戒断联系起来的病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.