Guo Xia , Qingfa Pan , Qin Pan , Yanduo Li , Defeng Yu , Jianfei Zhu
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引用次数: 0
Abstract
High-throughput on-line Raman detection has become commonplace in pharmaceutical and PAT. This has increased the demand for efficient, parallel spectral detection. In this work, a method of adjusting the optical structure parameters through multi-field theory is proposed to realize the detector accepting two spectral information from the light source at the same time. By combining two Raman probes and two customized Y-fibers, Raman spectra of two samples at the same laser power can be acquired simultaneously online. Compared with the multi-channel Raman spectroscopy detection system based on microscope device and multiple Raman spectroscopy coupling system, the measurement time and cost are greatly reduced. Thus, dual-channel Raman spectroscopy detection devices provide a cost and time-saving method for modern high-throughput on-line Raman detection.
高通量在线拉曼检测已成为制药和 PAT 领域的普遍现象。这就增加了对高效、并行光谱检测的需求。在这项工作中，提出了一种通过多场理论调整光学结构参数的方法，以实现探测器同时接受来自光源的两种光谱信息。通过将两个拉曼探针和两根定制的 Y 型光纤组合在一起，可以同时在线获取相同激光功率下两个样品的拉曼光谱。与基于显微镜设备和多拉曼光谱耦合系统的多通道拉曼光谱检测系统相比，测量时间和成本大大降低。因此，双通道拉曼光谱检测装置为现代高通量在线拉曼检测提供了一种节省成本和时间的方法。
期刊介绍：
Vibrational Spectroscopy provides a vehicle for the publication of original research that focuses on vibrational spectroscopy. This covers infrared, near-infrared and Raman spectroscopies and publishes papers dealing with developments in applications, theory, techniques and instrumentation.
The topics covered by the journal include:
Sampling techniques,
Vibrational spectroscopy coupled with separation techniques,
Instrumentation (Fourier transform, conventional and laser based),
Data manipulation,
Spectra-structure correlation and group frequencies.
The application areas covered include:
Analytical chemistry,
Bio-organic and bio-inorganic chemistry,
Organic chemistry,
Inorganic chemistry,
Catalysis,
Environmental science,
Industrial chemistry,
Materials science,
Physical chemistry,
Polymer science,
Process control,
Specialized problem solving.
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