Gamma Knife radiosurgery for the treatment of trigeminal neuralgia: A single center-experience

IF 0.7 4区医学 Q4 NEUROSCIENCES

Neurocirugia Pub Date : 2024-09-01 DOI:10.1016/j.neucir.2024.03.003

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引用次数: 0

Abstract

Introduction and objectives

We aimed to assess the outcomes of patients with trigeminal neuralgia (TGN) who underwent Gamma Knife radiosurgery (GKRS).

Materials and methods

Fifty-three patients with typical TGN underwent GKRS from May 2012 until December 2022. Among these patients, 45 patients who were follow-up for at least 12 months were included in the study. A mean dose of 87.5 Gy (range, 80–90) was administered to the trigeminal nerve. Postoperatively, outcome was considered excellent if the patient was pain- and medication-free.

Results

The mean symtpom duration was 9.53 years, and the mean patient age was 59.8 years (range, 34–85). The mean follow-up period was 46.8 months (range, 12–127 months). 46.7% of patients had a history of previous surgical interventions. A single nerve division was affected in 14 patients (31.1%), and multiple divisions were affected in 31 patients (68.9%). The rate of initial pain relief was 80%. Hypoesthesia in the area of trigeminal nerve developed in 30 (66.7%). Twenty patients (44.4%) exhibited excellent results within 72.4 months. Recurrence occurred in 11 patients (24.4%) with 27.6 months.

Conclusions

Our results suggest that GKRS is a safe and effective procedure. Thus, it is an attractive first- and second-line treatment choice for TGN.

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伽玛刀放射外科治疗三叉神经痛：单个中心的经验

材料和方法自 2012 年 5 月至 2022 年 12 月，53 名典型三叉神经痛患者接受了伽玛刀放射外科手术。在这些患者中，有 45 名患者接受了至少 12 个月的随访。三叉神经的平均治疗剂量为87.5 Gy（范围为80-90）。术后，如果患者无痛且无需服药，则认为疗效极佳。平均随访时间为 46.8 个月（12-127 个月）。46.7%的患者曾接受过手术治疗。14名患者（31.1%）的神经只受单一分支影响，31名患者（68.9%）的神经受多个分支影响。最初的疼痛缓解率为 80%。30名患者（66.7%）出现三叉神经区域感觉减退。20 名患者（44.4%）在 72.4 个月内取得了良好的效果。结论我们的结果表明，GKRS 是一种安全有效的手术。我们的研究结果表明，GKRS 是一种安全有效的手术，因此是治疗 TGN 的一种极具吸引力的一线和二线治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocirugia 医学-神经科学

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

60 days

期刊介绍： Neurocirugía is the official Journal of the Spanish Society of Neurosurgery (SENEC). It is published every 2 months (6 issues per year). Neurocirugía will consider for publication, original clinical and experimental scientific works associated with neurosurgery and other related neurological sciences. All manuscripts are submitted for review by experts in the field (peer review) and are carried out anonymously (double blind). The Journal accepts works written in Spanish or English.