Prevalence of SARS-CoV-2 Antibodies in Kosovo-Wide Population-Based Seroepidemiological Study

IF 4.3 4区医学 Q1 INFECTIOUS DISEASES

Influenza and Other Respiratory Viruses Pub Date : 2024-09-03 DOI:10.1111/irv.70004

Naser Ramadani, Sanije Hoxha-Gashi, Dafina Gexha-Bunjaku, Arijana Kalaveshi, Xhevat Jakupi, Isme Humolli, Aisling Vaughan, Richard Pebody, Pranvera Kacaniku-Gunga, Violeta Jashari

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Abstract

Background

Seroprevalence studies have proven to be an important tool in tracking the progression of the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to measure the seroprevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the general population of Kosovo by gender, age group and region and among asymptomatic people.

Method

The Institute of Public Health of Kosovo conducted a cross-sectional population-based survey, aligned with the protocols of the WHO Unity Studies, from the beginning of May to the end of June 2021.

Results

The survey covered a total of 2204 people with a response rate of 91.8% (41.9% [923] males and 51.2% [1281] females). In May to June 2021, the prevalence of antibodies in the overall population (IgG antibodies ≥ 1.1) was 37.0%. Seroprevalence was 34.4% in men and 38.9% in women (p < 0.05), with the highest percentage (48.7%) found in the 60–69 years' age group. The overall prevalence of acute IgM antibodies (IgM ≥ 1.1) was 1% (95% CI: 0.7%–1.5%), with no significant difference between genders and the highest prevalence among participants of 60–69 years of age (1.6%; 95% CI: 0.7%–3.6%).

Conclusion

A high prevalence of antibodies against SARS-CoV-2 was found in Kosovo before the start of the vaccination campaign. However, the results of the survey suggested that, by the end of June 2021, a desirable level of protection from the SARS-CoV-2 virus had not been reached.

Abstract Image

查看原文本刊更多论文

科索沃全人口血清流行病学研究中的 SARS-CoV-2 抗体流行率。

背景：事实证明，血清流行率研究是跟踪 2019 年冠状病毒病（COVID-19）大流行进展情况的重要工具。本研究的目的是按性别、年龄组、地区和无症状人群测量科索沃普通人群中严重急性呼吸系统综合征冠状病毒2（SARS-CoV-2）抗体的血清流行率：方法：2021 年 5 月初至 6 月底，科索沃公共卫生研究所按照世界卫生组织统一研究的规程，进行了一次以人口为基础的横断面调查：调查共涉及 2204 人，回复率为 91.8%（男性为 41.9% [923]，女性为 51.2% [1281]）。2021 年 5 月至 6 月，总体人群的抗体流行率（IgG 抗体≥ 1.1）为 37.0%。男性和女性的血清流行率分别为 34.4%和 38.9%（P 结论）：在疫苗接种活动开始之前，科索沃的 SARS-CoV-2 抗体流行率很高。然而，调查结果表明，到 2021 年 6 月底，SARS-CoV-2 病毒的保护水平尚未达到理想水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Influenza and Other Respiratory Viruses 医学-病毒学

CiteScore

7.20

自引率

4.50%

发文量

120

审稿时长

6-12 weeks

期刊介绍： Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases. Influenza and Other Respiratory Viruses is an Open Access journal. Copyright on any research article published by Influenza and Other Respiratory Viruses is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified.