Gyoungeun Park, Jeong-Hyun Moon, Seo-Hyun Park, Joo-Hee Kim, Byung-Kwan Seo, Seung-Deok Lee, Won-Suk Sung
{"title":"The Effectiveness and Safety of Yi Shen Juan Bi Pill on Rheumatoid Arthritis: a Protocol for Systematic Review and/or Meta-Analysis.","authors":"Gyoungeun Park, Jeong-Hyun Moon, Seo-Hyun Park, Joo-Hee Kim, Byung-Kwan Seo, Seung-Deok Lee, Won-Suk Sung","doi":"10.51507/j.jams.2024.17.4.116","DOIUrl":null,"url":null,"abstract":"<p><strong>Importance: </strong>The Yi Shen Juan Bi (YSJB) pill has been used to treat rheumatoid arthritis (RA), with several studies reporting its anti-inflammatory effects and ability to prevent bone destruction. However, the lack of evidence regarding the effectiveness and toxicity of individual components of YSJB limits its widespread use.</p><p><strong>Objective: </strong>This protocol outlines a systematic review and/or meta-analysis to evaluate the effectiveness and safety of YSJB.</p><p><strong>Data resources: </strong>We will search worldwide electronic databases, including MEDLINE, Cochrane Library, China National Knowledge Infrastructure, Wanfang, CiNii, J-STAGE, KoreaMed, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, Korea Institute of Science and Technology Information, and Oriental Medicine Advanced Searching Integrated System. In addition, we will conduct manual searches, and, if necessary, contact authors directly. The search will cover publications until June 2024.</p><p><strong>Study selection: </strong>We will select randomized controlled trials (RCTs) that compare the use of YSJB for the treatment of RA against other treatments.</p><p><strong>Study extraction and synthesis: </strong>Data from the selected RCTs will be extracted, including sample size, patient characteristics, intervention details, and outcome measures. We will perform a meta-analysis using Review Manager software.</p><p><strong>Main outcome(s) and measure(s): </strong>The primary outcome measures will include disease activity scores such as effective rate, swollen joint count, tender joint count, and morning stiffness. Secondary outcome measures will include blood test results and adverse events.</p><p><strong>Results: </strong>The results will reveal the effectiveness and safety of YSJB for the treatment of RA.</p><p><strong>Conclusions: </strong>and Relevance: The findings will provide an evidence-based review of the use of YSJB for RA.S.</p>","PeriodicalId":46854,"journal":{"name":"Journal of Acupuncture and Meridian Studies","volume":"17 4","pages":"116-122"},"PeriodicalIF":0.9000,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Acupuncture and Meridian Studies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51507/j.jams.2024.17.4.116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Importance: The Yi Shen Juan Bi (YSJB) pill has been used to treat rheumatoid arthritis (RA), with several studies reporting its anti-inflammatory effects and ability to prevent bone destruction. However, the lack of evidence regarding the effectiveness and toxicity of individual components of YSJB limits its widespread use.
Objective: This protocol outlines a systematic review and/or meta-analysis to evaluate the effectiveness and safety of YSJB.
Data resources: We will search worldwide electronic databases, including MEDLINE, Cochrane Library, China National Knowledge Infrastructure, Wanfang, CiNii, J-STAGE, KoreaMed, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, Korea Institute of Science and Technology Information, and Oriental Medicine Advanced Searching Integrated System. In addition, we will conduct manual searches, and, if necessary, contact authors directly. The search will cover publications until June 2024.
Study selection: We will select randomized controlled trials (RCTs) that compare the use of YSJB for the treatment of RA against other treatments.
Study extraction and synthesis: Data from the selected RCTs will be extracted, including sample size, patient characteristics, intervention details, and outcome measures. We will perform a meta-analysis using Review Manager software.
Main outcome(s) and measure(s): The primary outcome measures will include disease activity scores such as effective rate, swollen joint count, tender joint count, and morning stiffness. Secondary outcome measures will include blood test results and adverse events.
Results: The results will reveal the effectiveness and safety of YSJB for the treatment of RA.
Conclusions: and Relevance: The findings will provide an evidence-based review of the use of YSJB for RA.S.
期刊介绍:
The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine. Manuscripts should fall into one of the categories: topical review, original research paper, brief ... click here for full Aims & Scope The Journal of Acupuncture and Meridian Studies is a quarterly, peer-reviewed journal featuring high-quality studies related to basic and clinical acupuncture and meridian research. It also includes new paradigm of integrative research, covering East–West and traditional–modern medicine.