Predictive value of isolated very low QRS voltage in tilt-table test for neurally mediated syncope.

IF 2.3 Q2 MEDICINE, GENERAL & INTERNAL
SAGE Open Medicine Pub Date : 2024-08-27 eCollection Date: 2024-01-01 DOI:10.1177/20503121241272661
Haichao Chen, Yiwei Cao, Lei Liang, Yan Gao, Jing Feng, Le Zhang, Lingxia Shi, Fengjun Chang, Gong Cheng, Haoyu Wu
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Abstract

Objective: The cause of syncope is generally determined based on clinical manifestations. There has been little discussion about the value of electrocardiograms for diagnosing neurally mediated syncope. The aim of this study was to test the predictive value of the isolated very low QRS voltage in tilt-table testing for suspected neurally mediated syncope in a Chinese population.

Methods: This retrospective study enrolled patients with suspected neurally mediated syncope. Tilt-table testing was a part of the diagnostic examination. Each patient underwent echocardiography and electrocardiogram. isolated very low QRS voltage referred to a voltage of ⩽0.3 mV for the QRS complex in an isolated frontal lead or ⩽0.7 mV for the QRS complex in an isolated precordial lead.

Results: In total, 157 patients were included in the tilt-table testing positive group, and 242 patients were included in the tilt-table testing negative group. Compared with the testing negative group, the testing positive group had more patients with isolated very low QRS voltage in the frontal leads (p < 0.001). Moreover, for patients with isolated very low QRS voltage in the precordial leads, no significant difference was noted between the testing positive group and testing negative group (p = 0.289). Isolated very low QRS voltage in the frontal leads demonstrated 84.08% sensitivity and 74.38% specificity for a positive tilt-table testing response. The area under the curve of isolated very low QRS voltage for a positive tilt-table testing response in frontal leads was 0.806 (p < 0.0001).

Conclusion: In patients with suspected neurally mediated syncope, isolated very low QRS voltage in the frontal leads is a parameter that can predict a positive tilt-table testing response. The presence of isolated very low QRS voltage in frontal leads can serve as a parameter for evaluating syncope patients.

倾斜台试验中孤立极低 QRS 电压对神经介导晕厥的预测价值。
目的:晕厥的病因一般根据临床表现来确定。关于心电图在诊断神经介导性晕厥方面的价值,目前还鲜有讨论。本研究旨在测试倾斜台测试中孤立极低 QRS 电压对中国人群中疑似神经介导性晕厥的预测价值:这项回顾性研究招募了疑似神经介导性晕厥患者。倾斜台测试是诊断检查的一部分。孤立极低 QRS 电压是指孤立额前导联的 QRS 波群电压为 ⩽0.3 mV 或孤立心前导联的 QRS 波群电压为 ⩽0.7 mV:倾斜台测试阳性组共有 157 名患者,倾斜台测试阴性组共有 242 名患者。与倾斜台测试阴性组相比,倾斜台测试阳性组中额前导联出现孤立性极低 QRS 波群的患者更多(P = 0.289)。额导联孤立极低 QRS 电压对倾斜台测试阳性反应的敏感性为 84.08%,特异性为 74.38%。额导联孤立极低 QRS 电压对倾斜试验阳性反应的曲线下面积为 0.806(p 结论:额导联孤立极低 QRS 电压对倾斜试验阳性反应的敏感性和特异性分别为 84.08%和 74.38%:对于疑似神经介导的晕厥患者,额导联的孤立极低 QRS 电压是一个可以预测倾斜台测试阳性反应的参数。额导联出现孤立的极低 QRS 电压可作为评估晕厥患者的一个参数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
SAGE Open Medicine
SAGE Open Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
3.50
自引率
4.30%
发文量
289
审稿时长
12 weeks
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