Integrated diagnostics, complex biomarkers, and a new frontier for tissue pathology

IF 3.9 2区 医学 Q2 CELL BIOLOGY
Histopathology Pub Date : 2024-08-29 DOI:10.1111/his.15298
Manuel Salto-Tellez, Catarina Eloy, Arvydas Laurinavicius, Filippo Fraggetta
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引用次数: 0

Abstract

What will be the next disruptive technology that will change pathology's routine practice again? In this editorial we make a case for the need of more complex biomarkers in oncology diagnostics, to match the inherent complexity of cancer biology. This complexity will be achieved by the validation of technology able to generate more meaningful biological datapoints (epitomized in tissue pathology by technologies such as multiplex immunofluorescence) and, more important, by the systematic analysis of multimodal technology outputs with artificial intelligence tools, which is the essence of integrated diagnostics. While describing these processes, the authors highlight the pivotal role that histopathology will play, once again, in yet another transformation in diagnostics.

综合诊断、复杂生物标记和组织病理学的新领域
下一个将再次改变病理学常规实践的颠覆性技术会是什么?在这篇社论中,我们认为肿瘤诊断需要更复杂的生物标记物,以适应癌症生物学的内在复杂性。要实现这种复杂性,需要对能够生成更有意义的生物数据点的技术进行验证(组织病理学中的多重免疫荧光等技术就是缩影),更重要的是,需要利用人工智能工具对多模态技术的输出结果进行系统分析,这是综合诊断的精髓所在。在描述这些过程时,作者强调了组织病理学将在诊断学的又一次变革中再次发挥关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Histopathology
Histopathology 医学-病理学
CiteScore
10.20
自引率
4.70%
发文量
239
审稿时长
1 months
期刊介绍: Histopathology is an international journal intended to be of practical value to surgical and diagnostic histopathologists, and to investigators of human disease who employ histopathological methods. Our primary purpose is to publish advances in pathology, in particular those applicable to clinical practice and contributing to the better understanding of human disease.
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