Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion

IF 12.2 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gut Microbes Pub Date : 2024-08-29 DOI:10.1080/19490976.2024.2390176

Lingyi Wu, Jianchun Zhou, An Zhou, Yuanyuan Lei, Li Tang, Shiping Hu, Sumin Wang, Xu Xiao, Qiao Chen, Dianji Tu, Cheng Lu, Yi Lai, Yiding Li, Xiao Zhang, Bo Tang, Shiming Yang

引用次数: 0

Abstract

Gut microbiota dysbiosis is involved in cholestatic liver diseases. However, the mechanisms remain to be elucidated. The purpose of this study was to examine the effects and mechanisms of Lactobaci...

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嗜酸乳杆菌通过抑制胆汁酸合成和促进胆汁酸排泄改善胆汁淤积性肝损伤

肠道微生物群失调与胆汁淤积性肝病有关。然而，其机制仍有待阐明。本研究旨在探讨乳酸菌对胆汁淤积性肝病的影响及其机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gut Microbes Medicine-Microbiology (medical)

CiteScore

18.20

自引率

3.30%

发文量

196

审稿时长

10 weeks

期刊介绍： The intestinal microbiota plays a crucial role in human physiology, influencing various aspects of health and disease such as nutrition, obesity, brain function, allergic responses, immunity, inflammatory bowel disease, irritable bowel syndrome, cancer development, cardiac disease, liver disease, and more. Gut Microbes serves as a platform for showcasing and discussing state-of-the-art research related to the microorganisms present in the intestine. The journal emphasizes mechanistic and cause-and-effect studies. Additionally, it has a counterpart, Gut Microbes Reports, which places a greater focus on emerging topics and comparative and incremental studies.