The complex non-genetic inheritance of complex traits

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-08-29 DOI:10.1038/s41576-024-00770-6

Merly C. Vogt

引用次数: 0

Abstract

Merly C. Vogt recalls a seminal paper by Greer et al., who demonstrated the transgenerational inheritance of longevity, a complex trait, in Caenorhabditis elegans by manipulating the trimethylation of histone H3 lysine 4 (H3K4me3) in the parental generation.

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复杂性状的非遗传复杂性

Merly C. Vogt 回顾了 Greer 等人的一篇开创性论文，他们通过操纵亲代中组蛋白 H3 赖氨酸 4 的三甲基化（H3K4me3），证明了秀丽隐杆线虫（Caenorhabditis elegans）长寿这一复杂性状的跨代遗传。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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