Recent advances in hydrogels applications for tissue engineering and clinical trials

IF 3.4 3区环境科学与生态学 Q3 CELL & TISSUE ENGINEERING

Regenerative Therapy Pub Date : 2024-06-01 DOI:10.1016/j.reth.2024.08.015

Leila Rezakhani , Maliheh Gharibshahian , Majid Salehi , Sepehr Zamani , Zahra Abpeikar , Omid Ghaderzadeh , Morteza Alizadeh , Alireza Masoudi , Nariman Rezaei , Danial Cheraghali

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引用次数: 0

Abstract

Hydrogels are biomolecules made of artificial and natural polymers. Their quasi-three-dimensional structure has created unique features. They are very hydrophilic, and in addition to the high inflation rate, they also have excellent water maintenance capacity, biodegradability, biocompatibility, and strong mechanical properties. These properties are used in many tissue engineering applications. All these features have made these scaffolds widely used as attractive structures in the world of tissue engineering and regeneration medicine. In addition to research, scaffolds entered the field of medicine and are expected to play a significant role in the repair of many tissues in the future. This study aims to review the various polymers involved in hydrogel fabrication and their application in the repair of diverse tissues and clinical trials.

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水凝胶应用于组织工程和临床试验的最新进展

水凝胶是由人造和天然聚合物制成的生物大分子。其准三维结构具有独特的功能。它们具有很强的亲水性，除了高膨胀率外，还具有出色的保水能力、生物降解性、生物相容性和较强的机械性能。这些特性在许多组织工程应用中都得到了广泛应用。所有这些特性使这些支架在组织工程和再生医学领域被广泛用作有吸引力的结构。除研究外，支架还进入了医学领域，有望在未来许多组织的修复中发挥重要作用。本研究旨在回顾水凝胶制造中涉及的各种聚合物及其在不同组织修复和临床试验中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Regenerative Therapy Engineering-Biomedical Engineering

CiteScore

6.00

自引率

2.30%

发文量

106

审稿时长

49 days

期刊介绍： Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine. Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.