{"title":"A low-grade mucinous neoplasm arising within an ovarian mature cystic teratoma: a case report","authors":"Donna O’Dwyer, Steven Nottley, Sarah Bell","doi":"10.1016/j.mpdhp.2024.06.006","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>A 52-year old female presenting with an ovarian mass underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Intra-operatively there was large volume </span>ascites<span> containing mucin and hair. Subsequent pathological examination of the ovarian mass revealed a low-grade mucinous neoplasm arising within a mature cystic teratoma (MCT). This was associated with </span></span>pseudomyxoma peritonei<span><span> (PMP) and is a rare entity recognized by the World Health Organisation. These tumours resemble their appendiceal counterpart and therefore diagnosis is achieved with immunohistochemistry and thorough morphological assessment to exclude a collision tumour. Additionally, the appendix should be examined to confirm ovarian origin. Identification of these neoplasms is crucial as reasonable outcomes can be achieved following appropriate referral for ongoing management which includes complete surgical cytoreduction and </span>hyperthermic intraperitoneal chemotherapy (HIPEC).</span></p></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"30 9","pages":"Pages 530-532"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231724000987","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 52-year old female presenting with an ovarian mass underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Intra-operatively there was large volume ascites containing mucin and hair. Subsequent pathological examination of the ovarian mass revealed a low-grade mucinous neoplasm arising within a mature cystic teratoma (MCT). This was associated with pseudomyxoma peritonei (PMP) and is a rare entity recognized by the World Health Organisation. These tumours resemble their appendiceal counterpart and therefore diagnosis is achieved with immunohistochemistry and thorough morphological assessment to exclude a collision tumour. Additionally, the appendix should be examined to confirm ovarian origin. Identification of these neoplasms is crucial as reasonable outcomes can be achieved following appropriate referral for ongoing management which includes complete surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC).
期刊介绍：
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.
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