Investigation of the Effect of Compression Pressure in Contact OCT Imaging on the Measurement of Epidermis Thickness.

Zhiying Xie, Yaping Shi, Agathe Marmin, Ruikang K Wang
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Abstract

Optical coherence tomography (OCT) is a noninvasive 3D imaging technique that offers significant advantages over traditional microscopy and biopsy in measuring epidermal thickness (ET) when assessing skin conditions. However, OCT imagining is often required to be in a contact mode for mitigating the issues of subject movement and uneven skin topology. It is not known whether the contact would affect the ability of ET measurements. In this study, we investigate the relationship between the contact pressure applied and the ET measurements. We observed progressive deformation in the epidermis with the increase of compression forces, where a notable decrease of up to 13% in ET measurement and 70% decrease in capillary vessels was noted when imaging was in contact mode. We also observed 8.1% less deformation properties in scar tissue than in nearby healthy tissue. Our study underscored the importance of controlled pressure in contact imaging mode, which is often neglected.

研究接触式 OCT 成像中的压缩压力对表皮厚度测量的影响
光学相干断层扫描(OCT)是一种无创三维成像技术,与传统的显微镜和活组织检查相比,它在评估皮肤状况时测量表皮厚度(ET)方面具有显著优势。不过,OCT 成像通常需要在接触模式下进行,以减少受试者移动和皮肤拓扑不均匀的问题。目前还不清楚接触模式是否会影响 ET 测量的能力。在本研究中,我们研究了接触压力与 ET 测量之间的关系。我们观察到表皮随着压力的增加而逐渐变形,在接触模式下成像时,ET 测量值明显下降达 13%,毛细血管下降 70%。我们还观察到疤痕组织的变形特性比附近的健康组织低 8.1%。我们的研究强调了在接触成像模式下控制压力的重要性,而这一点往往被忽视。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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