Influence of the leukoreduction moment of blood components on the clinical outcomes of transfused patients in the emergency department.

IF 1.2 Q3 NURSING

Revista Brasileira De Enfermagem Pub Date : 2024-08-26 eCollection Date: 2024-01-01 DOI:10.1590/0034-7167-2023-0293

Natasha Dejigov Monteiro da Silva, Ana Catharina Herbst, Milena Raquel André, Lilia de Souza Nogueira

{"title":"Influence of the leukoreduction moment of blood components on the clinical outcomes of transfused patients in the emergency department.","authors":"Natasha Dejigov Monteiro da Silva, Ana Catharina Herbst, Milena Raquel André, Lilia de Souza Nogueira","doi":"10.1590/0034-7167-2023-0293","DOIUrl":null,"url":null,"abstract":"Objectives: to investigate the influence of the leukoreduction moment (preor post-storage) of blood components on the clinical outcomes of patients transfused in the emergency department.Methods: retrospective cohort study of patients aged 18 years or older who received preor post-storage leukoreduced red blood cell or platelet concentrate in the emergency department and remained in the institution for more than 24 hours. A generalized mixed-effects model was applied in the analyses.Results: in a sample of 373 patients (63.27% male, mean age 54.83) and 643 transfusions (69.98% red blood cell), it was identified that the leukoreduction moment influenced the length of hospital stay (p<0.009), but was not dependent on the transfused blood component (p=0.124). The leukoreduction moment had no effect (p>0.050) on transfusion reactions, healthcare-associated infections, or mortality.Conclusions: patients who received pre-storage leukoreduced blood components in the emergency department had a shorter length of hospital stay.","PeriodicalId":21200,"journal":{"name":"Revista Brasileira De Enfermagem","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11346908/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Brasileira De Enfermagem","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/0034-7167-2023-0293","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"NURSING","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: to investigate the influence of the leukoreduction moment (preor post-storage) of blood components on the clinical outcomes of patients transfused in the emergency department.

Methods: retrospective cohort study of patients aged 18 years or older who received preor post-storage leukoreduced red blood cell or platelet concentrate in the emergency department and remained in the institution for more than 24 hours. A generalized mixed-effects model was applied in the analyses.

Results: in a sample of 373 patients (63.27% male, mean age 54.83) and 643 transfusions (69.98% red blood cell), it was identified that the leukoreduction moment influenced the length of hospital stay (p<0.009), but was not dependent on the transfused blood component (p=0.124). The leukoreduction moment had no effect (p>0.050) on transfusion reactions, healthcare-associated infections, or mortality.

Conclusions: patients who received pre-storage leukoreduced blood components in the emergency department had a shorter length of hospital stay.

查看原文本刊更多论文

血液成分的白细胞还原力矩对急诊科输血患者临床疗效的影响。

目的：研究血液成分的减白时刻（储存前或储存后）对急诊科输血患者临床结果的影响。方法：对在急诊科接受储存前或储存后减白红细胞或血小板浓缩物的 18 岁或 18 岁以上患者进行回顾性队列研究，并在该机构停留超过 24 小时。结果：在373名患者（63.27%为男性，平均年龄54.83岁）和643次输血（69.98%为红细胞）的样本中，发现白细胞还原时刻对输血反应、医疗相关感染或死亡率的住院时间有影响（P0.050）。结论：在急诊科接受储存前白细胞还原血液成分的患者住院时间较短。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista Brasileira De Enfermagem NURSING-

CiteScore

2.30

自引率

7.70%

发文量

477

审稿时长

21 weeks

期刊介绍： The Revista Brasileira de Enfermagem created in 1932, March 20 is the official publication of the Associação Brasileira de Enfermagem (Brazilian Nursing Association) has as purpose to disseminate the scientific production from different nursing interest areas of knowledge, including those which express the political project of the Association. The Revista Brasileira de Enfermagem is the oldest journal of the Brazilian nursing. Its first title was "Annaes de Enfermagem" from 1932 to 1941, being entitled Anais de Enfermagem" until 1955, when its title was changed to the current.