Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in wild rats in Egypt during 2023.

IF 8.4 2区医学 Q1 IMMUNOLOGY

Emerging Microbes & Infections Pub Date : 2024-12-01 Epub Date: 2024-08-30 DOI:10.1080/22221751.2024.2396874

Omnia Kutkat, Mokhtar Gomaa, Yassmin Moatasim, Ahmed El Taweel, Mina Nabil Kamel, Mohamed El Sayes, Mohamed GabAllah, Ahmed Kandeil, Pamela P McKenzie, Richard J Webby, Ghazi Kayali, Mohamed Ahmed Ali, Rabeh El-Shesheny

引用次数: 0

Abstract

We detected highly pathogenic avian influenza A(H5N1) virus in wild rats collected from a rural area in Giza, Egypt, near poultry farms, markets, and backyard flocks. Sequence and phylogenetic analyses indicated that the virus from the rats belonged to clade 2.3.4.4b, which has been the predominant virus genotype circulating in Egypt and worldwide since 2021-2022. Active surveillance of avian influenza viruses in wild and domestic mammals is recommended to prevent further spread to mammals and humans.

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2023 年期间埃及野鼠中的高致病性禽流感病毒 H5N1 2.3.4.4b 支系。

我们在埃及吉萨农村地区家禽养殖场、市场和散养鸡群附近采集的野鼠体内检测到了高致病性甲型禽流感（H5N1）病毒。序列和系统进化分析表明，野鼠体内的病毒属于 2.3.4.4b 支系，该支系是 2021-2022 年以来在埃及和全球流行的主要病毒基因型。建议对野生和家养哺乳动物中的禽流感病毒进行积极监测，以防止病毒进一步传播给哺乳动物和人类。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Emerging Microbes & Infections IMMUNOLOGY-MICROBIOLOGY

CiteScore

26.20

自引率

2.30%

发文量

276

审稿时长

20 weeks

期刊介绍： Emerging Microbes & Infections is a peer-reviewed, open-access journal dedicated to publishing research at the intersection of emerging immunology and microbiology viruses. The journal's mission is to share information on microbes and infections, particularly those gaining significance in both biological and clinical realms due to increased pathogenic frequency. Emerging Microbes & Infections is committed to bridging the scientific gap between developed and developing countries. This journal addresses topics of critical biological and clinical importance, including but not limited to: - Epidemic surveillance - Clinical manifestations - Diagnosis and management - Cellular and molecular pathogenesis - Innate and acquired immune responses between emerging microbes and their hosts - Drug discovery - Vaccine development research Emerging Microbes & Infections invites submissions of original research articles, review articles, letters, and commentaries, fostering a platform for the dissemination of impactful research in the field.

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