Thomas Sun, Brian Shaw, Jorge Cusco, Jacqueline Kropf, Tirrell Johnson, S. J. Carlan
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引用次数: 0
Abstract
Vitamin C deficiency, otherwise known as scurvy, is one the oldest known diseases. Although its prevalence has substantially diminished, certain populations such as smokers, alcoholics, elderly, and those with malabsorptive syndromes remain at risk. Deficiency presents with perifollicular hemorrhage, corkscrew hairs, and petechiae that can evolve into ecchymoses and purpura. Diagnosis starts with clinical suspicion and is confirmed with plasma and leukocyte ascorbic acid levels. Early suspicion is key. Treatment with vitamin C offers an excellent prognosis and avoids unnecessary workup for differential diagnoses. In our case, a 45-year-old male alcoholic with progressively worsening symptoms was found to have scurvy. Treatment was initiated with vitamin C supplementation, and he had remarkable improvement in his symptoms within weeks. This case demonstrates that scurvy is not a disease of history and must be considered in modern medicine, especially as homelessness with concomitant poor nutrition continues to increase.
维生素 C 缺乏症又称坏血病,是已知的最古老的疾病之一。虽然其发病率已大大降低,但某些人群,如吸烟者、酗酒者、老年人和患有消化不良综合征的人仍有患病风险。缺乏症表现为毛囊周围出血、鸡冠状毛发和瘀斑,可发展为瘀点和紫癜。诊断始于临床怀疑,并通过血浆和白细胞抗坏血酸水平进行确诊。早期怀疑是关键。使用维生素 C 治疗可获得良好的预后,并避免不必要的鉴别诊断检查。在我们的病例中,一名 45 岁的男性酗酒者因症状逐渐加重而被发现患有坏血病。在开始补充维生素 C 的治疗后,他的症状在几周内就得到了明显改善。本病例表明,坏血病并不是一种历史疾病,现代医学必须考虑到这一点,尤其是在无家可归并伴随营养不良的情况不断增加的情况下。
期刊介绍:
The European Journal of Clinical Nutrition (EJCN) is an international, peer-reviewed journal covering all aspects of human and clinical nutrition. The journal welcomes original research, reviews, case reports and brief communications based on clinical, metabolic and epidemiological studies that describe methodologies, mechanisms, associations and benefits of nutritional interventions for clinical disease and health promotion.
Topics of interest include but are not limited to:
Nutrition and Health (including climate and ecological aspects)
Metabolism & Metabolomics
Genomics and personalized strategies in nutrition
Nutrition during the early life cycle
Health issues and nutrition in the elderly
Phenotyping in clinical nutrition
Nutrition in acute and chronic diseases
The double burden of ''malnutrition'': Under-nutrition and Obesity
Prevention of Non Communicable Diseases (NCD)