A meta-analysis on the neuropsychological correlates of Borderline Personality Disorder: An update

IF 7.5 1区医学 Q1 BEHAVIORAL SCIENCES

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-22 DOI:10.1016/j.neubiorev.2024.105860

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引用次数: 0

Abstract

Previous research on Borderline Personality Disorder (BPD) demonstrated dysfunction across a broad range of cognitive domains. However, the limited number of neuropsychological studies on BPD and their occasionally conflicting results have precluded a clear characterization of the neuropsychological features associated with this personality disorder. Therefore, the main aim of the present study is to provide an updated overview of neuropsychological functions related to BPD. A meta-analysis of 36 studies was performed, comparing the performance of BPD patients and healthy controls (HCs) across several cognitive domains. Significant differences between BPD patients and HCs in multiple cognitive domains were found. The smallest effect size was observed for general executive function, while the largest effect sizes were found in the long-term spatial memory and inhibition domains. In conclusion, the neuropsychological profile of BPD, characterized by deficits in inhibition as well as attention, memory, and executive functions, can result in difficulties in performing everyday activities. Accordingly, assessing neuropsychological functions could assist clinicians in developing more targeted non-pharmacological treatments.

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关于边缘型人格障碍神经心理学相关因素的荟萃分析：最新进展。

以往对边缘型人格障碍（BPD）的研究表明，该病在认知领域存在广泛的功能障碍。然而，由于有关 BPD 的神经心理学研究数量有限，而且研究结果有时相互矛盾，因此无法清楚地描述与这种人格障碍相关的神经心理学特征。因此，本研究的主要目的是提供与 BPD 相关的神经心理学功能的最新概述。本研究对 36 项研究进行了荟萃分析，比较了 BPD 患者和健康对照组（HCs）在多个认知领域的表现。结果发现，BPD 患者和健康对照组在多个认知领域存在显著差异。一般执行功能的效应大小最小，而长期空间记忆和抑制领域的效应大小最大。总之，BPD 的神经心理特征以抑制、注意力、记忆和执行功能的缺陷为特征，会导致患者在进行日常活动时遇到困难。因此，对神经心理功能进行评估有助于临床医生开发更有针对性的非药物治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuroscience and Biobehavioral Reviews 医学-行为科学

CiteScore

14.20

自引率

3.70%

发文量

466

审稿时长

6 months

期刊介绍： The official journal of the International Behavioral Neuroscience Society publishes original and significant review articles that explore the intersection between neuroscience and the study of psychological processes and behavior. The journal also welcomes articles that primarily focus on psychological processes and behavior, as long as they have relevance to one or more areas of neuroscience.