RETRACTION: α-Synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

IF 4.4 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

FASEB Journal Pub Date : 2024-08-23 DOI:10.1096/fj.

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引用次数: 0

Abstract

RETRACTION: J.-H. Seo, J.-C. Rah, S. H. Choi, J. K. Shin, K. Min, H.-S. Kim, C. H. Park, S. Kim, E.-M. Kim, S.-H. Lee, S. Lee, S. Won Suh, and Y.-H. Suh, “Α-Synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway,” The FASEB Journal 16, no. 13 (2002): 1–20, https://doi.org/10.1096/fj.02-0041fje.

The above article, published online on September 5, 2002, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Loren E. Wold; the Federation of American Societies for Experimental Biology; and Wiley Periodicals LLC. The retraction has been agreed upon following an investigation into concerns raised by a third party which revealed inappropriate image duplications within the western blot lanes of Figure 5B and across the lanes of Figures 4A,C and 5A,B. Due to the number and the level of errors identified in the published figures, the editors have lost confidence in the presented data and consider the conclusions substantially compromised. The authors have been informed about the concerns, but did not provide an explanation and due to the time elapsed since publication the original raw data were not available.

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回归：α-突触核蛋白通过 Bcl-2 家族表达和 PI3/Akt 激酶途径调节神经元存活。

撤回：J.-H. Seo, J.-C.Seo, J.-C.Rah、S. H. Choi、J. K. Shin、K. Min、H.-S.Kim, C. H. Park, S. Kim, E.-M.Kim, S.-H. Lee, S. Lee, S. Kim, E.-M.Lee, S. Lee, S. Won Suh, and Y.-H. Suh, "Α-Syn.Suh, "Α-Synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway," The FASEB Journal 16, no：1-20, https://doi.org/10.1096/fj.02-0041fje.上述文章于 2002 年 9 月 5 日在线发表于 Wiley Online Library (wileyonlinelibrary.com)，经期刊主编 Loren E. Wold、美国实验生物学学会联合会和 Wiley Periodicals LLC 协议，该文章已被撤回。第三方提出的问题显示，图 5B 的 Western 印迹泳道内以及图 4A,C 和 5A,B 的泳道间存在不适当的图像重复。由于在发表的图中发现的错误数量之多、程度之严重，编辑们对所提供的数据失去了信心，认为结论大打折扣。作者已被告知这些问题，但没有做出解释，而且由于发表时间已过，无法获得原始数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

FASEB Journal 生物-生化与分子生物学

CiteScore

9.20

自引率

2.10%

发文量

6243

审稿时长

3 months

期刊介绍： The FASEB Journal publishes international, transdisciplinary research covering all fields of biology at every level of organization: atomic, molecular, cell, tissue, organ, organismic and population. While the journal strives to include research that cuts across the biological sciences, it also considers submissions that lie within one field, but may have implications for other fields as well. The journal seeks to publish basic and translational research, but also welcomes reports of pre-clinical and early clinical research. In addition to research, review, and hypothesis submissions, The FASEB Journal also seeks perspectives, commentaries, book reviews, and similar content related to the life sciences in its Up Front section.