Procedural abortion, provider-initiated preterm delivery and survival in pregnant people with cancer: A population-based cohort study.

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-08-21 DOI:10.1111/1471-0528.17937

Amy Metcalfe, Zoe F Cairncross, Joel G Ray, Lorraine Shack, Gregg Nelson, Christine M Friedenreich, Khokan Sikdar, Sarka Lisonkova, Carly A McMorris, Parveen Bhatti, Deshayne B Fell

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引用次数: 0

Abstract

Objective: To assess whether procedural-induced abortion or provider-initiated preterm delivery are associated with improved survival in pregnant people with cancer.

Design: Retrospective population-based cohort study.

Setting: Provinces of Alberta and Ontario, Canada, 2003-2016.

Population: Females aged 18-50 years diagnosed with cancer at <20 weeks' (for the assessment of procedural-induced abortion) or <37 weeks' gestation (for the assessment of provider-initiated delivery).

Methods: Cox proportional hazard models assessed all-cause mortality in relation to procedural-induced abortion and provider-initiated preterm delivery, adjusting for cancer site, stage at diagnosis and age. Meta-analysis pooled the results across both provinces.

Main outcome measures: All cause mortality.

Results: There were 512 pregnant people diagnosed with cancer at <20 weeks' gestation and 782 diagnosed with cancer at <37 weeks' gestation. Neither procedural-induced abortion (adjusted hazard ratio [aHR] = 1.39, 95% CI: 0.32-6.17) nor provider-initiated preterm delivery (aHR = 1.17, 95% CI: 0.76-1.81) were associated with improved survival following adjustment for age, stage at diagnosis and cancer site.

Conclusions: Neither procedural-induced abortion nor provider-initiated preterm birth was associated with improved survival in pregnant people diagnosed with cancer; however, these obstetric interventions are highly personal decisions best decided by the pregnant person in consultation with their care providers.

查看原文本刊更多论文

癌症孕妇的程序性流产、提供者引发的早产和存活率：基于人群的队列研究。

目的评估程序性流产或提供者引发的早产是否与癌症孕妇生存率的提高有关：设计：基于人群的回顾性队列研究：背景：加拿大艾伯塔省和安大略省，2003-2016年：方法：Cox 比例危险模型评估妊娠期癌症患者的生存率：Cox比例危险模型评估了与程序性流产和提供者引发的早产有关的全因死亡率，并对癌症部位、诊断分期和年龄进行了调整。Meta 分析汇总了两个省份的结果：主要结果测量：全因死亡率：结论：共有 512 名孕妇确诊患有癌症：程序性人工流产和医疗服务提供者引发的早产都与确诊癌症孕妇生存率的提高无关；然而，这些产科干预措施是高度个人化的决定，最好由孕妇与医疗服务提供者协商决定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.