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Targeting Glioblastoma: Efficacy of Ruthenium-Based Drugs.

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
ACS Applied Electronic Materials Pub Date : 2024-09-16 Epub Date: 2024-08-20 DOI:10.1021/acs.chemrestox.4c00188
Puthiyavalappil Rasin, Sravan Sangeeth Surendran, Karthik K S, Jebiti Haribabu, Anandaram Sreekanth
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Abstract

Ruthenium compounds offer improved selectivity and fewer side effects compared to platinum-based drugs in glioblastoma treatment. Insights into their interactions with transferrin suggest targeted drug delivery, while photoactivated chemotherapy is a novel cytotoxic approach in tumor tissues.

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针对胶质母细胞瘤：钌基药物的疗效。
与铂类药物相比，钌化合物在治疗胶质母细胞瘤方面具有更好的选择性和更少的副作用。对钌化合物与转铁蛋白相互作用的深入研究表明，钌化合物具有靶向给药作用，而光激活化疗则是肿瘤组织中的一种新型细胞毒疗法。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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来源期刊
ACS Applied Electronic Materials
ACS Applied Electronic Materials Multiple-
CiteScore
7.20
自引率
4.30%
发文量
567
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