TFH cell responses endure in human lymph nodes after vaccination

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2024-08-20 DOI:10.1038/s41590-024-01935-5

Cody S. Nelson, Peter T. Sage

引用次数: 0

Abstract

Longitudinal sampling of human lymph nodes using fine-needle aspiration after influenza or SARS-CoV-2 vaccination reveals substantial durability and transcriptional reprogramming of follicular helper T cells over time.

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接种疫苗后，人体淋巴结中的 TFH 细胞反应持续存在

在接种流感疫苗或 SARS-CoV-2 疫苗后，使用细针穿刺法对人体淋巴结进行纵向取样，结果显示滤泡辅助 T 细胞随着时间的推移具有很强的持久性并发生了转录重编程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.