Advancing Longevity: Exploring Antiaging Pharmaceuticals in Contemporary Clinical Trials Amid Aging Dynamics.

Rejuvenation research Pub Date : 2024-09-04 DOI:10.1089/rej.2024.0040

Murali Krishna Moka, Melvin George, D K Sriram

{"title":"Advancing Longevity: Exploring Antiaging Pharmaceuticals in Contemporary Clinical Trials Amid Aging Dynamics.","authors":"Murali Krishna Moka, Melvin George, D K Sriram","doi":"10.1089/rej.2024.0040","DOIUrl":null,"url":null,"abstract":"<p><p>Aging is an inevitable biological process that significantly impacts human health, leading to a decline in cellular function and an increase in cellular damage. This study elucidates the burgeoning potential of antiaging pharmaceuticals in mitigating the thriving burden of chronic conditions linked to advancing age. It underscores the pivotal role of these pharmacotherapeutic agents in fostering longevity free from debilitating age-related afflictions, notably cardiovascular disorders, neoplastic processes, and neurodegenerative pathologies. While commendable strides have been made evident in preclinical models, it is crucial to thoroughly investigate their effectiveness and safety in human groups. In addition, ethical concerns about fair access, societal impacts, and careful resource distribution are significant in discussions about developing and using antiaging medications. By approaching the development and utilization of antiaging medications with diligence and foresight, we can strive toward a future where individuals can enjoy extended lifespans free from the debilitating effects of age-related ailments.</p>","PeriodicalId":94189,"journal":{"name":"Rejuvenation research","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rejuvenation research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/rej.2024.0040","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Aging is an inevitable biological process that significantly impacts human health, leading to a decline in cellular function and an increase in cellular damage. This study elucidates the burgeoning potential of antiaging pharmaceuticals in mitigating the thriving burden of chronic conditions linked to advancing age. It underscores the pivotal role of these pharmacotherapeutic agents in fostering longevity free from debilitating age-related afflictions, notably cardiovascular disorders, neoplastic processes, and neurodegenerative pathologies. While commendable strides have been made evident in preclinical models, it is crucial to thoroughly investigate their effectiveness and safety in human groups. In addition, ethical concerns about fair access, societal impacts, and careful resource distribution are significant in discussions about developing and using antiaging medications. By approaching the development and utilization of antiaging medications with diligence and foresight, we can strive toward a future where individuals can enjoy extended lifespans free from the debilitating effects of age-related ailments.

查看原文本刊更多论文

促进长寿：在老龄化动态中探索当代临床试验中的抗衰老药物。

衰老是一个不可避免的生物过程，会严重影响人类健康，导致细胞功能下降和细胞损伤增加。这项研究阐明了抗衰老药物在减轻与年龄增长相关的慢性疾病造成的沉重负担方面的巨大潜力。它强调了抗衰老药物在促进长寿、避免衰老相关疾病（尤其是心血管疾病、肿瘤过程和神经退行性病变）方面的关键作用。虽然在临床前模型方面取得了值得称道的进展，但彻底研究这些药物在人类群体中的有效性和安全性至关重要。此外，在有关开发和使用抗衰老药物的讨论中，公平获取、社会影响和谨慎的资源分配等伦理问题也非常重要。通过以勤奋和前瞻性的态度对待抗衰老药物的开发和使用，我们可以努力实现这样一个未来，即人们可以享受更长的寿命，免受与年龄有关的疾病的衰弱影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Rejuvenation research

自引率

0.00%

发文量