Value of hepatic artery digital subtraction angiography in the detection of small hepatocellular carcinoma lesions

IF 4.4 3区医学 Q2 ENVIRONMENTAL SCIENCES

Environmental Toxicology Pub Date : 2024-08-20 DOI:10.1002/tox.24316

Tao Bai, Shaolong Lu, Jie Chen, Jiazhou Ye, Xiaobo Wang, Zhihong Tang, Hongyuan Fu, Lequn Li, Feixiang Wu

{"title":"Value of hepatic artery digital subtraction angiography in the detection of small hepatocellular carcinoma lesions","authors":"Tao Bai, Shaolong Lu, Jie Chen, Jiazhou Ye, Xiaobo Wang, Zhihong Tang, Hongyuan Fu, Lequn Li, Feixiang Wu","doi":"10.1002/tox.24316","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To compare the detection rates of hepatic artery digital subtraction angiography (HA-DSA) and magnetic resonance imaging (MRI) gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-DTPA) and MRI gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-EOB-DTPA) for small (diameter ≤2 cm) hepatocellular carcinoma (HCC) lesions.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A prospective analysis of patients admitted to the Tumor Hospital of Guangxi Medical University between January 1, 2015, and December 30, 2016, was conducted. The detection rates of the three methods were analyzed. The diameter of small HCC lesions detected using HA-DSA and MRI-Gd-EOB-DTPA were evaluated. The diagnostic value of HCC Barcelona staging for HA-DSA was analyzed.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>For 107 small lesions detected in 57 patients, the detection rates of HA-DSA and MRI-Gd-DTPA were 86.0% (92/107) and 71.0% (76/107), respectively (<i>p</i> < .05). Of 77 small lesions detected in 42 patients using MRI-Gd-EOB-DTPA and HA-DSA, 67 were detected using HA-DSA, all of which had a rich blood supply, and 72 were detected using MRI-Gd-EOB-DTPA. The minimum diameter of lesions detected using MRI-Gd-EOB-DTPA was approximately 0.4 cm, whereas that of lesions detected using HA-DSA was approximately 0.5 cm. After HA-DSA, a change in the Barcelona staging occurred in 33.3% (62/186) of cases but not after MRI-Gd-DTPA; HA-DSA was significantly better than MRI-Gd-DTPA for staging (<i>p</i> = .03).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>HA-DSA and MRI-Gd-EOB-DTPA have high diagnostic values for the detection of small HCC lesions, which is helpful for accurate staging of HCC and provides the most valuable information for patient treatment and prognosis.</p>\n </section>\n </div>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"39 10","pages":"4754-4762"},"PeriodicalIF":4.4000,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Toxicology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/tox.24316","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

To compare the detection rates of hepatic artery digital subtraction angiography (HA-DSA) and magnetic resonance imaging (MRI) gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-DTPA) and MRI gadolinium diethylenetriaminepentaacetic acid (MRI-Gd-EOB-DTPA) for small (diameter ≤2 cm) hepatocellular carcinoma (HCC) lesions.

Methods

A prospective analysis of patients admitted to the Tumor Hospital of Guangxi Medical University between January 1, 2015, and December 30, 2016, was conducted. The detection rates of the three methods were analyzed. The diameter of small HCC lesions detected using HA-DSA and MRI-Gd-EOB-DTPA were evaluated. The diagnostic value of HCC Barcelona staging for HA-DSA was analyzed.

Results

For 107 small lesions detected in 57 patients, the detection rates of HA-DSA and MRI-Gd-DTPA were 86.0% (92/107) and 71.0% (76/107), respectively (p < .05). Of 77 small lesions detected in 42 patients using MRI-Gd-EOB-DTPA and HA-DSA, 67 were detected using HA-DSA, all of which had a rich blood supply, and 72 were detected using MRI-Gd-EOB-DTPA. The minimum diameter of lesions detected using MRI-Gd-EOB-DTPA was approximately 0.4 cm, whereas that of lesions detected using HA-DSA was approximately 0.5 cm. After HA-DSA, a change in the Barcelona staging occurred in 33.3% (62/186) of cases but not after MRI-Gd-DTPA; HA-DSA was significantly better than MRI-Gd-DTPA for staging (p = .03).

Conclusion

HA-DSA and MRI-Gd-EOB-DTPA have high diagnostic values for the detection of small HCC lesions, which is helpful for accurate staging of HCC and provides the most valuable information for patient treatment and prognosis.

查看原文本刊更多论文

肝动脉数字减影血管造影在检测小肝癌病灶中的价值。

目的比较肝动脉数字减影血管造影（HA-DSA）和磁共振成像（MRI）二乙烯三胺五乙酸钆（MRI-Gd-DTPA）和二乙烯三胺五乙酸钆（MRI-Gd-EOB-DTPA）对肝细胞癌（HCC）小病灶（直径≤2 cm）的检出率：对广西医科大学附属肿瘤医院2015年1月1日至2016年12月30日期间收治的患者进行前瞻性分析。分析了三种方法的检出率。评估了使用HA-DSA和MRI-Gd-EOB-DTPA检测到的HCC小病灶的直径。分析了HA-DSA对HCC巴塞罗那分期的诊断价值：在 57 名患者中发现的 107 个小病灶中，HA-DSA 和 MRI-Gd-DTPA 的检出率分别为 86.0% (92/107)和 71.0% (76/107)（PHA-DSA和MRI-Gd-EOB-DTPA对检测HCC小病灶具有很高的诊断价值，有助于对HCC进行准确分期，为患者的治疗和预后提供最有价值的信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Environmental Toxicology 环境科学-毒理学

CiteScore

7.10

自引率

8.90%

发文量

261

审稿时长

4.5 months

期刊介绍： The journal publishes in the areas of toxicity and toxicology of environmental pollutants in air, dust, sediment, soil and water, and natural toxins in the environment.Of particular interest are: Toxic or biologically disruptive impacts of anthropogenic chemicals such as pharmaceuticals, industrial organics, agricultural chemicals, and by-products such as chlorinated compounds from water disinfection and waste incineration; Natural toxins and their impacts; Biotransformation and metabolism of toxigenic compounds, food chains for toxin accumulation or biodegradation; Assays of toxicity, endocrine disruption, mutagenicity, carcinogenicity, ecosystem impact and health hazard; Environmental and public health risk assessment, environmental guidelines, environmental policy for toxicants.