Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications

IF 4.8 3区化学 Q1 CHEMISTRY, MEDICINAL

Natural Products and Bioprospecting Pub Date : 2024-08-20 DOI:10.1007/s13659-024-00466-8

Mukul Shyam, Evan Prince Sabina

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Abstract

Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the realm of traditional Chinese medicine for a wide range of medicinal applications. The herb is rich in bioactive metabolites with therapeutic potential, encompassing polyphenolic antioxidants in its leaves, and flavonoids and fructo-oligosaccharides in its underground parts. Nutraceuticals originating from botanical sources such as Arctium lappa provide supplementary health advantages alongside their nutritional content and have demonstrated effectiveness in the prevention and management of specific ailments. The utilization of Arctium lappa root extract has exhibited encouraging outcomes in addressing hepatotoxicity induced by cadmium, lead, chromium, and acetaminophen, ameliorating liver damage and oxidative stress. Additionally, the root extract displays properties such as antidiabetic, hypolipidemic, aphrodisiac, anti-rheumatic, anti-Alzheimer, and various other pharmacological actions.

Graphical abstract

Abstract Image

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利用牛蒡根的力量：药理特性和治疗应用综述。

牛蒡（Arctium lappa）被广泛认为是牛蒡，是一种多年生植物，在传统中药领域具有广泛的药用价值。牛蒡富含具有治疗潜力的生物活性代谢物，叶片中含有多酚抗氧化剂，地下部分含有类黄酮和果寡糖。源自牛蒡等植物资源的保健食品除营养成分外，还具有补充保健的优势，在预防和治疗特定疾病方面已证明十分有效。在解决镉、铅、铬和对乙酰氨基酚引起的肝毒性方面，使用牛蒡根提取物已取得令人鼓舞的成果，可改善肝损伤和氧化应激。此外，牛蒡根提取物还具有抗糖尿病、降血脂、壮阳、抗风湿、抗老年痴呆等多种药理作用。

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来源期刊

Natural Products and Bioprospecting CHEMISTRY, MEDICINAL-

CiteScore

8.30

自引率

2.10%

发文量

审稿时长

13 weeks

期刊介绍： Natural Products and Bioprospecting serves as an international forum for essential research on natural products and focuses on, but is not limited to, the following aspects: Natural products: isolation and structure elucidation Natural products: synthesis Biological evaluation of biologically active natural products Bioorganic and medicinal chemistry Biosynthesis and microbiological transformation Fermentation and plant tissue cultures Bioprospecting of natural products from natural resources All research articles published in this journal have undergone rigorous peer review. In addition to original research articles, Natural Products and Bioprospecting publishes reviews and short communications, aiming to rapidly disseminate the research results of timely interest, and comprehensive reviews of emerging topics in all the areas of natural products. It is also an open access journal, which provides free access to its articles to anyone, anywhere.