Environmental Influences on Atopic Eczema.

Wismmy Lee, Fihr Chaudhary, Devendra K Agrawal
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Abstract

The health outcomes of an individual are shaped by a combination of genetic predisposition and environmental influences. While some diseases stem solely from environmental factors, others like atopic eczema, also known as neurodermatitis or atopic dermatitis, are multifaceted, with environmental variables playing a significant role in its initiation and severity. Atopic eczema is a prevalent chronic condition observed globally, particularly in Western industrialized nations where its prevalence is estimated to range from 2.5% to 3.5% in adults and 10% to 15% among children. The increasing incidence of atopic eczema in industrialized countries over recent decades suggests that this trend may be due to environmental changes rather than genetic predispositions. Therefore, by thoroughly examining environmental factors and their role in atopic dermatitis, one may be able to gain a better understanding of its disease pattern and develop possible preventative measures. This article provides a comprehensive analysis of how the surrounding environment contributes to the pathogenesis of atopic eczema.

环境对特应性湿疹的影响。
一个人的健康状况是由遗传倾向和环境影响共同决定的。有些疾病完全源于环境因素,而另一些疾病,如特应性皮炎(又称神经性皮炎或异位性皮炎),则是多方面的,环境变量在其发病和严重程度上起着重要作用。特应性湿疹是全球普遍存在的慢性疾病,尤其是在西方工业化国家,据估计成人发病率为 2.5% 至 3.5%,儿童发病率为 10% 至 15%。近几十年来,特应性湿疹在工业化国家的发病率不断上升,这表明这一趋势可能是由于环境变化而非遗传所致。因此,通过深入研究环境因素及其在特应性皮炎中的作用,人们或许能更好地了解其发病模式,并制定可能的预防措施。本文全面分析了周围环境对特应性湿疹发病机制的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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