Recent advances on the influence of fipronil on insect behavior

IF 5.8 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2024-08-13 DOI:10.1016/j.cois.2024.101251

引用次数: 0

Abstract

Fipronil, a pesticide widely used to control agricultural and household insect pests, blocks insect GABA_A and glutamate (GluCl) ionotropic receptors, resulting in uncontrolled hyperexcitation and paralysis that eventually leads to death. The use of fipronil is controversial because unintentional exposure to this compound may contribute to the ongoing global decline of insect pollinator populations. Although the sublethal effects of fipronil have been linked to aberrant behavior and impaired olfactory learning in insects, the precise mechanisms involved in these responses remain unclear. In this article, we highlight recent studies that have investigated the interaction among different pathways involved in the ability of fipronil to modulate insect behavior, with particular emphasis on the role of GABAergic neurotransmission in fine-tuning the integration of sensorial responses and insect behavior. Recent findings suggest that fipronil can also cause functional alterations that affect synaptic organization and the availability of metal ions in the brain.

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氟虫腈对昆虫行为影响的最新进展。

氟虫腈是一种广泛用于控制农业和家庭害虫的杀虫剂，它能阻断昆虫的 GABAA 和谷氨酸（GluCl）离子受体，导致不受控制的过度兴奋和麻痹，最终导致死亡。氟虫腈的使用备受争议，因为无意中接触这种化合物可能会导致全球昆虫授粉者数量持续减少。虽然氟虫腈的亚致死效应与昆虫的异常行为和嗅觉学习受损有关，但这些反应的确切机制仍不清楚。在本文中，我们将重点介绍最近的一些研究，这些研究调查了氟虫腈调节昆虫行为的能力所涉及的不同途径之间的相互作用，并特别强调了 GABA 能神经传递在微调感官反应和昆虫行为的整合中的作用。最新研究结果表明，氟虫腈还能引起功能性改变，影响突触组织和大脑中金属离子的可用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.