{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.202490182","DOIUrl":null,"url":null,"abstract":"<p>3,4-Dihydroquinazoline frameworks which have frequently been encountered in natural products and bioactive molecules, prompted the development of creative pharmaceuticals owing to their prominent biological properties, such as trypanothione reductase inhibitor, Hepatitis B virus inhibitive activities, anticancer activities, <i>etc</i>. <i>De novo</i> assembling of chiral 3,4-dihydroquinazolines from simple chemical feedstocks via multicomponent reactions remains several great obstacles, and this scenario is capable of the divergent and flexible modulation of these skeletons which is urgently required for drug discovery. More details are discussed in the article by Yu <i>et al</i>. on page 2140—2146.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"42 18","pages":"2122"},"PeriodicalIF":5.5000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.202490182","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cjoc.202490182","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
3,4-Dihydroquinazoline frameworks which have frequently been encountered in natural products and bioactive molecules, prompted the development of creative pharmaceuticals owing to their prominent biological properties, such as trypanothione reductase inhibitor, Hepatitis B virus inhibitive activities, anticancer activities, etc. De novo assembling of chiral 3,4-dihydroquinazolines from simple chemical feedstocks via multicomponent reactions remains several great obstacles, and this scenario is capable of the divergent and flexible modulation of these skeletons which is urgently required for drug discovery. More details are discussed in the article by Yu et al. on page 2140—2146.
期刊介绍：
The Chinese Journal of Chemistry is an international forum for peer-reviewed original research results in all fields of chemistry. Founded in 1983 under the name Acta Chimica Sinica English Edition and renamed in 1990 as Chinese Journal of Chemistry, the journal publishes a stimulating mixture of Accounts, Full Papers, Notes and Communications in English.
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